In vitro anti-bacterial activity of Tinospora cordifolia leaf extract and its phytochemical screening

Praiwala, B.; S, Priyanka; Raghu, Nitya; Gopenath, N.; Gnanasekaran, Ashok; Muthusamy, Karthikeyan; Indumathi, R.; Ebrahim, Naushaad; Pugazhandhi, B.; Pradeep, Pranav N.; Ranjith, M. S.; Subramanian, B.; Basalingappa, Kanthesh M.

doi:10.3126/jbs.v5i2.23633

Cited by 9 publications

(5 citation statements)

References 9 publications

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“…Results of the present study could be comparable with the previous studies which were stated that the ethanol extracts of leaves of E. littorale showed the highest antimicrobial activity against tested bacterial strains ( (Agarwal et al, 2019); ethanol extract of T. cordifolia did not show much inhibitory activity against microbes (Prajwala et al, 2018); leaf aqueous extract of T. cordifolia exhibited maximum zone of inhibition against selected four bacteria (Gunda and Kommidi, 2020); the aqueous and methanol leaf extract of G. sylvestre showed significant antibacterial activity (Beverly and Sudarsanam, 2013) and Methanol extract of G. sylvestre showed good antibacterial activity with the high inhibition zones (Kishor Naidu et al, 2013). Present study results were slightly different from previous studies of these selected plants.…”

Section: Resultssupporting

confidence: 92%

Comparative <em>In Vitro</em> antimicrobial activity of selected four medicinal plant leaves

2022

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In the treatment of diabetes mellitus, the traditional medical system of Sri Lanka has demonstrated to be far more effective, with less side effects and lower costs than modern synthetic medications. Ethnobotanical research is also necessary to learn about the world's traditional usage for treating chronic illness. Therefore, the present evaluation was aimed to compare the antimicrobial activity between the ethanolic leaves extracts of Murraya koenigii, Tinospora cordifolia, Enicostemma littorale and Gymnema sylvestre which are commonly found in Jaffna District against three different bacterial species such as Staphylococcus sp., Enterococcus sp. and Escherichia coli sp. by determining zone of inhibition using agar well diffusion method and compared with standard antibiotics. All experiments were conducted in triplicate. The statistical analysis was carried out using one-way Analysis of variance and values were expressed as the mean ± standard deviation. Results showed all the tested leaf extracts showed promising antibacterial activity against all the bacterial strains which was comparable with positive control Streptomycin. E.littorale showed the highest zone of inhibition diameter against Enterococcus sp. (14.08±2.46 mm). M.koenigii showed the highest zone of inhibition diameter against Staphylococcus sp. (8.96±2.49 mm) and E.coli (9.67±0.996 mm). Present study determined that the ethanol leaf extracts of Murraya sp. and Enicostemma sp. showed the highest antibacterial activity than other two species against all tested bacteria. Therefore, E.littorale and Enicostemma sp. can be used for developing therapeutic agents for the treatment of infectious diseases caused by microbes in future.

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Section: Resultssupporting

confidence: 92%

Comparative <em>In Vitro</em> antimicrobial activity of selected four medicinal plant leaves

2022

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“…The antimicrobial activity was comparatively low in distilled water extract, and showed no zone of inhibition against E. coli and Klebsiella. Prajwala et al (2018) also inferred similar result of distilled water extract showing no antimicrobial property against E. coli. The extract was most effective on gram positive, S. aureus at all concentrations used.…”

Section: Antimicrobial Activity Of Samples Extractsmentioning

confidence: 54%

Antimicrobial Assessment and Phytochemical Screening of Medicinal Plants and Ganoderma lucidum.

Thapa

Maharjan

Tamang

et al. 2022

Int J Appl Sci Biotechnol

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Nepal has always relied on traditional medicinal plants, herbs, and mushrooms that are locally available to treat numerous diseases. This study thus aimed to explore the antimicrobial properties of the plants and fungi that are commonly used as traditional medicines. Antimicrobial properties of 5 plants (Curcuma caesia. Acorus calamus, Moringa oleifera, Terminalia chebula, and Tinospora cordifolia) and 1 fungus (Ganoderma lucidum) were screened against 4 ATCC bacterial culture (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae). The extracts were prepared using Soxhlet’s apparatus in two solvents, i.e. ethanol and distilled water. Out of which, distilled water of Acorus calamus had the highest percentage yield. All extracts showed antimicrobial properties against S. aureus. The highest potential was observed in the ethanolic extract of Curcuma caesia against S. aureus with the zone of inhibition of 22mm The ethanolic extract of Tinospora cordiofolia showed promising antimicrobial against gram-negative bacteria: E.coli, P. aeruginosa and K. pneumoniae with the zone of inhibition 15mm, 15mm and 14mm respectively. The distilled water extract of Acorus calamus showed the highest antimicrobial activity against P. aeruginosa with a zone of inhibition of 18mm. In the case of phytochemical screening, both the extracts of Tinospora cordiofolia showed the highest phytochemicals (Terpenoids, Saponins, Coumarin, Flavonoids, Alkaloids, and Tannins). The experiment confirmed the efficacy of selected plants and fungus extract as a natural antimicrobial against all the test organisms used, suggesting the possibility of employing them in novel drug development against the treatment of infectious diseases caused by the test organisms.

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“…The absorbance values of each aliquot prepared were determined from 290 nm to 320 nm at 5 nm intervals, using 90 % ethanol solution as a blank. The SPF was calculated using the following equation; SPF spectrophotometric = CF×SPF spectrophotometric = ∑ 320 290 EE (λ) Abs (λ) × CFWhere, CF = Correction factor (10) EE = Erythrogenic effect of radiation with wavelength (λ) Abs (λ) = Spectrophotometric absorbance values at wavelength The value of EE × I is constant (as shown in Table 2). 3,16,17 The results of all these characterization and evaluation parameters are given in section 8.…”

Section: Determination Of Sun Protection Factor (Spf)mentioning

confidence: 99%

Preparation and evaluation of herbal sunscreen creams

Mewada

Shah

2023

IJPCA

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Presently herbal sunscreens are widely used by almost everyone on this planet to prevent from harmful effects of UV radiation from sunlight. Herbals are preferable because of fewer side effects and a better safety profile. This study is about the preparation and evaluation of herbal sunscreen creams possessing anti-UV radiation effectiveness and anti-inflammatory properties. Creams were prepared from the extract of plant materials, such as respectively. Glycyrrhiza glabra, Tinospora cordifolia and Terminalia arjuna, total polyphenol and flavonoid content. Evaluation of prepared herbal sunscreen creams was performed on parameters such as organoleptic properties, pH, rancidity, spreadability and drug content. The effectiveness of the products was evaluated by measuring Sun Protection Factor (SPF). These products showed good spreadability, consistency, homogeneity, appearance, desired pH, ease of removal and no evidence of phase separation. Our formulation of sunscreen creams is considered to be effective sunscreen in healing, softening and rejuvenating the skin.

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In vitro anti-bacterial activity of Tinospora cordifolia leaf extract and its phytochemical screening

Cited by 9 publications

References 9 publications

Comparative <em>In Vitro</em> antimicrobial activity of selected four medicinal plant leaves

Comparative <em>In Vitro</em> antimicrobial activity of selected four medicinal plant leaves

Antimicrobial Assessment and Phytochemical Screening of Medicinal Plants and Ganoderma lucidum.

Preparation and evaluation of herbal sunscreen creams

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