2000
DOI: 10.1007/s002560000204
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In vitro and in vivo spin echo diffusion imaging characteristics of synovial fluid: potential non-invasive differentiation of inflammatory and degenerative arthritis

Abstract: Synovial fluid in degenerative arthritis shows less diffusion or free water movement than synovial fluid in inflammatory arthritis. Diffusion characteristics of synovial fluid may be used to predict the nature of the underlying form of arthritis in patients presenting with knee joint effusions.

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Cited by 19 publications
(9 citation statements)
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“…As there is some variability in recorded diffusion values, it is recommended to determine the mean of multiple ADC readings at different parts of an effusion in order to minimize the impact of the local regional variations in diffusion which appear to exist [36]. To prevent ADC values from susceptibility artifacts, ROIs should not be calculated from pleural fluid-lung interfaces and diaphragmatic regions.…”
Section: Discussionmentioning
confidence: 98%
“…As there is some variability in recorded diffusion values, it is recommended to determine the mean of multiple ADC readings at different parts of an effusion in order to minimize the impact of the local regional variations in diffusion which appear to exist [36]. To prevent ADC values from susceptibility artifacts, ROIs should not be calculated from pleural fluid-lung interfaces and diaphragmatic regions.…”
Section: Discussionmentioning
confidence: 98%
“…Diffusion-weighted magnetic resonance imaging has been used for diagnosis of diseases of the central nervous system for two decades [3,4]-being a particularly important tool in the diagnosis of ischemic stroke-and the musculoskeletal system for one decade [5,6]. During recent years, DWI of diseases of the lower abdomen, e.g.…”
Section: Introductionmentioning
confidence: 99%
“…Whereas diffusion-sensitized single-shot spin-echo echo planar imaging (EPI) sequences are now regarded as the standard approach for DWI and DTI of the brain, no such agreement exists with respect to DWI outside the brain. Several alternative techniques for DWI of musculoskeletal structures have been applied, including spin echo (SE) or stimulated echo sequences with navigator echo motion correction [17,21], line scan imaging techniques [27], MR sequences with radial k-space acquisition [18], steady-state free precession (SSFP) sequences [23], segmented (i.e., multi-shot) EPI sequences [22], and single-shot sequences based on the acquisition of a series of spin echoes, such as turbo spin echo (TSE) methods [25,26]. This last group appears especially promising for robust DWI examinations in clinical routine because these sequences are less motion-sensitive due to the single-shot approach and, at the same time, the acquisition of multiple spin echoes is less sensitive to susceptibility artifacts than the EPI readout.…”
Section: Introductionmentioning
confidence: 99%
“…Other clinical applications include the characterization of multiple sclerosis lesions, abscesses, and tumors of the brain [7][8][9][10]. DWI has also been performed outside the brain, e.g., in the abdominal organs (liver, kidneys, ovaries) [11][12][13][14] and in various musculoskeletal structures, such as muscle, synovial fluid, intervertebral discs, tumor tissue, and bone marrow [15][16][17][18][19][20][21][22][23][24][25][26][27][28]. Several of these studies indicate that DWI may be useful for the differentiation between benign and malignant lesions [11,21,23,25,26], between viable and necrotic tumor regions [29], or between tumor recurrences and post-therapeutic softtissue changes [19].…”
Section: Introductionmentioning
confidence: 99%