In vitro and in vivo acaricide action of juvenoid analogs produced from the chemical modification of Cymbopogon spp. and Corymbia citriodora essential oil on the cattle tick Rhipicephalus (Boophilus) microplus

Chagas, A. C. de S.; Domingues, Luciana Ferreira; Fantatto, Rafaela Regina; Giglioti, Rodrigo; Oliveira, M. C. de S.; Oliveira, Dariiela H.; Mano, Renata A.; Jacob, Raquel G.

doi:10.1016/j.vetpar.2014.06.030

Cited by 34 publications

(18 citation statements)

References 39 publications

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“…While ethical medicinal products (pharmaceuticals) have been widely investigated pharmacologically and toxicologically by commercial companies, the studies on medicinal plants are still rare (Couatre, 2004), particularly in the field of veterinary medicine. Nevertheless, documentation and validation of home-grown phytomedicines (as a substitute to orthodox drugs) against GI nematodes of small ruminants are being executed extensively by South Latin American, Asian and African researchers, yet their trials mostly encompass clinical studies without comprehensive phytochemical investigations (Chagas et al, 2014).…”

Section: Phytopharmacology and Phytotoxicology Of Medicinal Plantsmentioning

confidence: 99%

Phytotherapeutics: As anticipating substitutes to synthetic drugs in combating antinematicidal-resistant gastrointestinal nematodes of small ruminants

Hamad

Ahmed

et al. 2018

ZJPAS

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It has been narrated and postulated that various plants were utilized as therapeutic agents for the first time by the distinct primate "Neanderthal" (Homo neanderthalensis) between 60,000-80,000 years BC in the Kurdistan Region of Iraq (Agelarakis, 1993; Sommer, 1999; Hamad, 2012). Records attribute the use of medicinal plants to prehistoric Mesopotamian Civilizations (land between the two rivers of Tigris and Euphrates), in particular the Sumerians who dwelt modern over 5,000 years ago (Levetin and McMahon, 2003). It is noteworthy to mention that exploitation of herbal remedies was practiced by Chinese herbalists (Ergil et al., 2002) and Indian botanists (Aggarwal et al., 2007) around 2700 BC and 1900 BC, respectively. Ancient Greeks and Romans as well as Muslim scientists have also contributed to the use of phytomedicines (Iqbal et al., 2001). The recent decades have witnessed a distinct development in herbology by employing modern pharmacological techniques

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Section: Phytopharmacology and Phytotoxicology Of Medicinal Plantsmentioning

confidence: 99%

Phytotherapeutics: As anticipating substitutes to synthetic drugs in combating antinematicidal-resistant gastrointestinal nematodes of small ruminants

Hamad

Ahmed

et al. 2018

ZJPAS

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“…[60][61][62] A Npropargilamina 12a (3,7-dimetil-N-(prop-2-inil)oct-6-en-1-amina) tem ação como juvenóide contra as pupas de 67 A reação hetero-Diels-Alder entre as anilinas 9a-h e a mistura de isômeros dos 3-(feniltio)-citronelais 18 foi realizada em meio livre de solvente, utilizando SiO 2 /ZnCl 2 (10 %) como catalisador e sob irradiação de microondas ou a temperatura ambiente. A metodologia é seletiva para a formação dos isômeros trans (96:4) e os produtos foram obtidos com bons rendimentos.…”

Section: Esquema 8 Síntese De Octaidroacridinas 8 Em Glicerolunclassified

“…75,76 Estas substâncias apresentaram efeito antiplaquetário, o que indica um elevado potencial desta classe de compostos para o possível uso como agentes antitrombóticos. 49,54,57,61,65,77 Neste contexto, a metodologia de eneciclização do (R)-citronelal 1 (Esquema 2) foi aplicada diretamente no óleo essencial bruto de citronela (C. nardus), sem isolamento prévio do citronelal. 49 Quando o OE de citronela (contendo 45 % de (R)-citronelal 1) foi irradiado no micro-ondas (427 W) por 1 minuto, na presença de SiO 2 /ZnCl 2 (10 %), observou-se 10 0% de conversão ao (-)-isopulegol 2.…”

Section: Eugenolunclassified

Essential Oils as a Sustainable Raw Material for the Preparation of Products with Higher Value-Added

Jacob

2017

Rev. Virtual Quim.

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Abstract:The use of renewable feedstocks, which may substitute those derived from petroleum, is currently a great challenge in the chemical and pharmaceutical industries. However, plant essential oils (EOs) that have been studied for their biological activities, such as antioxidant, antimicrobial, antifungal and antinociceptive are generally regarded as safe additives maintaining the microbiological stability of foods. EOs are a mixture of natural volatile compounds, that are predominantly formed during the secondary metabolism in plants and commonly concentrated in the leaves, bark or fruits of aromatic plants. They are complex mixtures composed mainly of terpenes (hydrocarbons or oxygenated compounds) and phenylpropanoids, which can be used as a source of raw materials for fine chemicals industry. In recent years, researchers and industries have been focusing on the major compounds of EOs in order to use them as solvents or as bio-based building blocks adding value to this material derived from biomass.Keywords: Essential oil; bio-based compounds; biomass. ResumoO uso de matérias-primas renováveis, que podem substituir os derivados de petróleo, é atualmente um grande desafio para as indústrias químicas e farmacêuticas. No entanto, os óleos essenciais (OEs) de plantas que têm sido estudados pelas suas atividades biológicas, tais como antioxidante, antimicrobiana, antifúngica e antinociceptiva, são geralmente considerados como aditivos seguros para a manutenção da estabilidade microbiológica de alimentos. Os OEs são uma mistura de compostos voláteis naturais, que são formados durante o metabolismo secundário das plantas e geralmente concentrados nas folhas, casca ou frutos de plantas aromáticas. Eles são misturas complexas compostas principalmente de terpenos (hidrocarbonetos ou compostos oxigenados) e fenilpropanoides, que podem ser utilizados como uma fonte de matéria-prima para a indústria de química fina. Nos últimos anos, pesquisadores e indústrias estão focados nos componentes majoritários dos OEs, a fim de usá-los como solventes ou como blocos de construção de base biológica agregando valor a este material derivado de biomassa.

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“…It as an aromatic grass whose acaricidal properties have been attributed to the presence of monoterpenes such as citronellal, geraniol, limonene, etc. (Chagas et al 2014;Rodriguez-Vivas et al 2018).…”

Section: Introductionmentioning

confidence: 99%

Cymbopogon citratus essential oil-induced ultrastructural & morphological changes in the midgut, cuticle & Haller’s organ of the tick Haemaphysalis longicornis (Acari: Ixodidae)

Agwunobi

et al. 2020

saa

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Haemaphysalis longicornis Neumann is a widely distributed species known for its capacity to transmit pathogens of medical, public health, and veterinary importance. Due to the environmental contamination caused by synthetic acaricides, plant essential oils have emerged as a promising alternative to manage tick infestation. This study evaluated the ultrastructural and morphological changes induced by Cymbopogon citratus Stapf (lemongrass) essential oil on adult H. longicornis tick. The concentrations of lemongrass essential oil used for the treatment via the adult immersion test were from 10 to 40 mg/mL. The most significant alterations 24 h post-exposure include the proliferation of lysosomes, reduction in the number of the rough endoplasmic reticulum, disorganization of the microvilli, the disappearance of lipid droplets and hematin granules, and cytoplasmic vacuolization (midgut); a thinner endocuticle and epicuticle, the deletion of the subdivision’s demarcation of the procuticle, disfiguration of the lamellar arrangements of the exocuticle, and cytoplasmic vacuolization of the epithelial cells (integument); cracks on the sensilla sockets, the detachment of one or two sensilla in the anterior pit, and partial disfiguration of part of the slit’s edge (Haller’s organ). These results reflect the acaricidal properties of the essential oil and could be an alternative means of tick control.

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In vitro and in vivo acaricide action of juvenoid analogs produced from the chemical modification of Cymbopogon spp. and Corymbia citriodora essential oil on the cattle tick Rhipicephalus (Boophilus) microplus

Cited by 34 publications

References 39 publications

Phytotherapeutics: As anticipating substitutes to synthetic drugs in combating antinematicidal-resistant gastrointestinal nematodes of small ruminants

Phytotherapeutics: As anticipating substitutes to synthetic drugs in combating antinematicidal-resistant gastrointestinal nematodes of small ruminants

Essential Oils as a Sustainable Raw Material for the Preparation of Products with Higher Value-Added

<p class="Body"><strong><em>Cymbopogon citratus</em></strong><strong> essential oil-induced ultrastructural & morphological changes in the midgut, cuticle & Haller’s organ of the tick <em>Haemaphysalis longicornis</em> (Acari: Ixodidae)</strong></p>

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In vitro and in vivo acaricide action of juvenoid analogs produced from the chemical modification of Cymbopogon spp. and Corymbia citriodora essential oil on the cattle tick Rhipicephalus (Boophilus) microplus

Cited by 34 publications

References 39 publications

Phytotherapeutics: As anticipating substitutes to synthetic drugs in combating antinematicidal-resistant gastrointestinal nematodes of small ruminants

Phytotherapeutics: As anticipating substitutes to synthetic drugs in combating antinematicidal-resistant gastrointestinal nematodes of small ruminants

Essential Oils as a Sustainable Raw Material for the Preparation of Products with Higher Value-Added

<p class="Body"><strong><em>Cymbopogon citratus</em></strong><strong> essential oil-induced ultrastructural &amp; morphological changes in the midgut, cuticle &amp; Haller’s organ of the tick <em>Haemaphysalis longicornis</em> (Acari: Ixodidae)</strong></p>

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Product

Resources

About

<p class="Body"><strong><em>Cymbopogon citratus</em></strong><strong> essential oil-induced ultrastructural & morphological changes in the midgut, cuticle & Haller’s organ of the tick <em>Haemaphysalis longicornis</em> (Acari: Ixodidae)</strong></p>