In vitro and in vivo properties study of a novel 3D-printed absorbable pancreaticojejunostomy device made by melting blended poly(p-dioxanone)/poly(lactic acid)

Pan, Maoen; Xu, Zhilu; Luo, Wei; Yang, Yuanyuan; Teng, Tianhong; Lin, Jinxin; Huang, Heguang

doi:10.1016/j.matdes.2021.110088

Cited by 10 publications

(2 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We hypothesized that the higher blood impact from the ventricle may accelerate the degradation of PLLA framework and delay the endothelium coverage. Our results revealed that PDO with the presence of ether bonds favored endothelialization, consistent with previous studies [ 32 , 33 ], thus we chose PDO as a framework and PLLA as occlude membranes. Canine VSD models confirmed that the process of endothelium coverage was faster than that of absorption and the framework could retain its stability in 6 months, which is the time window for endothelium coverage.…”

Section: Discussionsupporting

confidence: 90%

A fully biodegradable polydioxanone occluder for ventricle septal defect closure

Kong

Liu

et al. 2023

Bioactive Materials

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 90%

A fully biodegradable polydioxanone occluder for ventricle septal defect closure

Kong

Liu

et al. 2023

Bioactive Materials

View full text Add to dashboard Cite

“…Compared to traditional manufacturing methods, 3D printing offers limitless design possibilities, enables the creation of complex shapes, and minimizes material waste. It is particularly suitable for the production of medical implants such as vascular stents, pancreaticojejunostomy devices, and bone tissue engineering scaffolds [ 4 , 27 , 28 , 29 ]. However, the durability of 3D-printed parts has not been thoroughly investigated or disclosed.…”

Section: Introductionmentioning

confidence: 99%

The Mechanical Properties and Degradation Behavior of 3D-Printed Cellulose Nanofiber/Polylactic Acid Composites

Zhang,

Cao,

Jiang

2023

Materials

View full text Add to dashboard Cite

Polylactic acid (PLA) has been widely used in many fields because of its good biodegradability, biocompatibility, and renewability. This work studied the degradation behavior and mechanical properties of cellulose nanofiber (CNF)/PLA composites. In vitro degradation experiments of 3D-printed samples were conducted at elevated temperatures, and the degradation characteristics were evaluated by mechanical tests, gel permeation chromatography (GPC), differential scanning calorimetric (DSC), and scanning electron microscope (SEM). The results indicated that the addition of CNF (0.5 wt%) accelerated the degradation rate of PLA. The decreases in number average molecular weight (Mn) and weight average molecular weight (Mw) of composites were 7.96% and 4.91% higher than that of neat PLA, respectively. Furthermore, the tensile modulus of composites was 18.4% higher than that of neat PLA, while the strength was 7.4% lower due to poor interfacial bonding between CNF and PLA. A mapping relationship between accelerated and normal degradation showed that the degradation experienced during 60 days at 37 °C was equivalent to that undergone during 14 days at 50 °C; this was achieved by examining the alteration in Mn. Moreover, the degradation process caused a notable deformation in the samples due to residual stress generated during the 3D printing process. This study provided valuable insights for investigating the in vitro degradation behavior of 3D-printed products.

show abstract

Structural, Thermal, Optical and Antibacterial Properties of Co-doped (Dy3+/Eu3+): PEG + PVA Novel Transparent Hybrid Films

Çoban

Diken

Doğan

et al. 2023

J Inorg Organomet Polym

View full text Add to dashboard Cite

In vitro and in vivo properties study of a novel 3D-printed absorbable pancreaticojejunostomy device made by melting blended poly(p-dioxanone)/poly(lactic acid)

Cited by 10 publications

References 44 publications

A fully biodegradable polydioxanone occluder for ventricle septal defect closure

A fully biodegradable polydioxanone occluder for ventricle septal defect closure

The Mechanical Properties and Degradation Behavior of 3D-Printed Cellulose Nanofiber/Polylactic Acid Composites

Structural, Thermal, Optical and Antibacterial Properties of Co-doped (Dy3+/Eu3+): PEG + PVA Novel Transparent Hybrid Films

Contact Info

Product

Resources

About