In Vitro and In Vivo Comparative Analysis of Differentially Expressed Genes and Signaling Pathways in Breast Cancer Cells on Interaction with Mesenchymal Stem Cells

Identification and validation of key genes in gastric cancer: insights from in silico analysis, clinical samples, and functional assays

“…Hypermethylation of the promoters has been linked to the down-regulation of these genes in breast, gastric, and colorectal cancers, contributing to tumor growth and invasion [56][57][58][59]. Conversely, hypomethylation of these genes has been observed in ovarian and lung cancers, leading to their overexpression and association with aggressive tumor phenotypes [60,61].…”