In Vitro and In Vivo Nephrotoxicity Evaluation of the Methanol Extract of Ficus deltoidea Jack Leaf
Abstract:Ficus deltoidea Jack leaves extract (FDLE) is rich in phytochemicals like alkaloids, phenolics, flavonoids, and steroids. These phytochemicals possess an excellent potential for medicinal applications. This study aimed to assess the kidney toxicity of FDLE through in vitro and in vivo methods. FDLE was obtained by maceration in methanol at room temperature for 24 h. The in vitro toxicity of FDLE at 10 -100 µg/mL was evaluated in Baby Hamster Kidney (BHK)-21fibroblast cells using the MTT assay method. The in vi… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.