In vitro and in vivo assessment of meadowsweet (Filipendula ulmaria) as anti-inflammatory agent

Katanić, Jelena; Boroja, Tatjana; Mihailović, Vladimir; Nikles, Stefanie; Pan, San-Po; Rosić, Gvozden; Selaković, Dragica; Joksimović, Jovana; Mitrović, Slobodanka; Bauer, Rudolf

doi:10.1016/j.jep.2016.10.015

Cited by 38 publications

(35 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous animal studies revealed that Filipendula species counteracted inflammatory processes and reduced pain (Katanić et al, 2016;Samardžić et al, 2016). A limited number of mechanistic in vitro experiments indicated that Filipendula extracts inhibited the classical pathway of the complement system (ESCOP, 2003), production of pro-inflammatory cytokines (Drummond et al, 2013) and expression of adhesion molecules (Vogl et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

Antioxidant, anti-inflammatory and gastroprotective activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench

Samardžić

Arsenijević

Božić

et al. 2018

Journal of Ethnopharmacology

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Antioxidant, anti-inflammatory and gastroprotective activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench

Samardžić

Arsenijević

Božić

et al. 2018

Journal of Ethnopharmacology

View full text Add to dashboard Cite

show abstract

“…However, use of the herb and flower are most frequently cited, and the European Medicine Agency has accepted it be sold as a ‘Traditional medicinal product for the supportive treatment of common cold, for the relief of minor articular pain’ based on ‘well-established use’ [ 76 ]. Both F. ulmaria aerial parts and roots have demonstrated anti-inflammatory activity in vitro and in vivo; although, the aerial parts exhibited a higher level of activity [ 77 ]. Salicylic acid and its derivatives are linked to its anti-inflammatory activity [ 77 , 78 ].…”

Section: Resultsmentioning

confidence: 99%

“…Both F. ulmaria aerial parts and roots have demonstrated anti-inflammatory activity in vitro and in vivo; although, the aerial parts exhibited a higher level of activity [ 77 ]. Salicylic acid and its derivatives are linked to its anti-inflammatory activity [ 77 , 78 ].…”

Section: Resultsmentioning

confidence: 99%

Are identities oral? Understanding ethnobotanical knowledge after Irish independence (1937–1939)

Shannon

Sasse

Sheridan

et al. 2017

J Ethnobiology Ethnomedicine

View full text Add to dashboard Cite

BackgroundThe Schools’ Folklore Scheme (1937–1939) was implemented at a pivotal time in Irelands’ political history. It resulted in a body of ethnological information that is unique in terms of when, why and how it was collected. This material consists of over 700,000 pages of information, including ethnomedicinal and ethnobotanical traditions, reflecting an oral identity that spans generations and that in many cases was not documented in writing until the 1930s. The intention of this study is to highlight the importance of the Schools’ Folklore Scheme and to demonstrate an ethnographic approach based on recollections of original participants of the scheme, to further understand the material in the collection and the impact it had on the participants.MethodsThis study involves an analysis of both oral and archival data. Eleven semi-structured interviews with original participants of the scheme were carried out between April and September 2016. Their corresponding schools’ archival contributions to the scheme were located, and ethnomedicinal information was analysed and compared with the participants’ recollections.ResultsThe majority of participants’ stated the scheme had a positive impact on them. Five participants’ recalled collecting ethnomedicinal information, and there was a direct correlation between three of the participants’ ethnomedicinal recollections and their entries in the archives. One third of all the ethnomedicinal entries analysed included the use of a plant. There were 191 plant mentions and 64 plant species named.ConclusionsContacting the original participants offers a novel approach of analysing this archival material. It provides a unique first-hand account of this historical initiative, an insight into how the scheme was implemented and how it impacted upon the children. The ethnomedicinal and ethnobotanical information provides an understanding of the medicinal practices in Ireland during the 1930s. The plant species that were both orally recalled by participants and documented in the archives are in keeping with key ethnomedicinal systems throughout the world.Electronic supplementary materialThe online version of this article (10.1186/s13002-017-0189-0) contains supplementary material, which is available to authorized users.

show abstract

“…Meadowsweet is indicated for the "supportive treatment of common cold" and also "for the relief of minor articular pain" (EMA, 2011). Evidence is available for antiinflammatory effects (Katani c et al, 2016), but overall, there are limited data supporting specific therapeutic benefits.…”

Section: Salicylate Drugs Of Botanical Originmentioning

confidence: 99%

Botanical drugs and supplements affecting the immune response in the time of COVID‐19: Implications for research and clinical practice

Brendler

Al‐Harrasi

Bauer

et al. 2020

Phytotherapy Research

Self Cite

View full text Add to dashboard Cite

In times of health crisis, including the current COVID‐19 pandemic, the potential benefit of botanical drugs and supplements emerges as a focus of attention, although controversial efficacy claims are rightly a concern. Phytotherapy has an established role in everyday self‐care and health care, but, since botanical preparations contain many chemical constituents rather than single compounds, challenges arise in demonstrating efficacy and safety. However, there is ample traditional, empirical, and clinical evidence that botanicals can offer some protection and alleviation of disease symptoms as well as promoting general well‐being. Newly emerging viral infections, specifically COVID‐19, represent a unique challenge in their novelty and absence of established antiviral treatment or immunization. We discuss here the roles and limitations of phytotherapy in helping to prevent and address viral infections, especially regarding their effects on immune response. Botanicals with a documented immunomodulatory, immunostimulatory, and antiinflammatory effects include adaptogens, Boswellia spp., Curcuma longa, Echinacea spp., Glycyrrhiza spp., medicinal fungi, Pelargonium sidoides, salicylate‐yielding herbs, and Sambucus spp. We further provide a clinical perspective on applications and safety of these herbs in prevention, onset, progression, and convalescence from respiratory viral infections.

show abstract

In vitro and in vivo assessment of meadowsweet (Filipendula ulmaria) as anti-inflammatory agent

Cited by 38 publications

References 48 publications

Antioxidant, anti-inflammatory and gastroprotective activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench

Antioxidant, anti-inflammatory and gastroprotective activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench

Are identities oral? Understanding ethnobotanical knowledge after Irish independence (1937–1939)

Botanical drugs and supplements affecting the immune response in the time of COVID‐19: Implications for research and clinical practice

Contact Info

Product

Resources

About