In-vitro and in-silico analyses of the thrombolytic potential of green kiwifruit
Reinhard Pinontoan,
Jonathan Suciono Purnomo,
Elvina Bella Avissa
et al.
Abstract:Cardiovascular diseases (CVDs), mainly caused by thrombosis complications, are the leading cause of mortality worldwide, making the development of alternative treatments highly desirable. In this study, the thrombolytic potential of green kiwifruit (Actinidia deliciosa cultivar Hayward) was assessed using in-vitro and in-silico approaches. The crude green kiwifruit extract demonstrated the ability to reduce blood clots significantly by 73.0 ± 1.12% (P < 0.01) within 6 h, with rapid degradation of Aα and Bβ … Show more
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