In vitro and in silico studies of enterobactin-inspired Ciprofloxacin and Fosfomycin first generation conjugates on the antibiotic resistant E. coli OQ866153
Mohamed T. Khazaal,
Ahmed H. I. Faraag,
Hoda H. El-Hendawy
Abstract:Background
The emergence of antimicrobial resistance in bacterial pathogens is a growing concern worldwide due to its impact on the treatment of bacterial infections. The "Trojan Horse" strategy has been proposed as a potential solution to overcome drug resistance caused by permeability issues.
Objective
The objective of our research was to investigate the bactericidal activity and mechanism of action of the "Trojan Horse" strategy using enterobact… Show more
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