In vitro and In silico Studies of Kayu Raja (Cassia fistula L.) Leaves Extract as Potential Antifungal Agent Against Candida albicans
Tan David Christian,
Kasiyati Kasiyati,
Tri Yuliani
et al.
Abstract:Candida albicans is one of the most common fungal species causing opportunistic infections, such as candidiasis. Candida albicans has the ability to produce and secrete hydrolytic enzymes, namely secrete aspartate protease (SAP). SAP3 is a virulence factor for mucosal or disseminated infections. Cassia fistula leaves have bioactive compounds that can be used as antimicrobial agents, such as hyperoside, delphin, epicatechin, isoquercitrin, and astragalin. This study aims to determine the potential of bioactive … Show more
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