In vitro activity of ciprofloxacin against aerobic bacteria isolated in a southern European hospital

Abstract

The activity of ciprofloxacin was evaluated against 1,204 isolates freshly isolated in Southern Europe, including 193 isolates of 10 species never studied before. Ciprofloxacin proved more active than other quinolones and very active in absolute terms against the 10 new species and showed against the other species an activity close to that reported for isolates from other geographic areas.

Use of a novel phosphatase test for simplified identification of species of the tribe Proteeae

“…This new and simple method for routine identification of species of Proteeae is likely to assume clinical importance, because strains from this group are often responsible for hospital-acquired infections, and the possibility of rapidly identifying them would be of great help in tracing the origin and spread of nosocomial outbreaks. Furthermore, highlevel and multiple antibiotic resistance is very frequent among P. stuartii, while it is quite uncommon among the other species of Proteeae (5,10,11,18). Thus, accurate identification to species level of Proteeae isolates is essential to avoid potentially misleading indications; even today, however, most of the surveys of susceptibilities to antimicrobial agents fail to fully separate the species of the tribe Proteeae, often splitting them into Proteus mirabilis, indolenegative Proteus species, and Providencia spp.…”

Synthesis and Antimicrobial Properties of Highly Cross-Linked pH-Sensitive Hydrogels through Gamma Radiation

“…Ciprofloxacin was used as a drug model since it has excellent antibacterial activity against a wide spectrum of Gram-positive and Gram-negative microorganisms [ 40 ]. Ciprofloxacin has similar activity against all Staphylococci [ 41 ]. Meanwhile, AgNPs are capable of attacking and eliminating some Gram-negative ( E. coli , Pseudomonas aeruginosa and Salmonella enterica ) and Gram-positive microorganisms ( S. aureus and Bacillus subtilis ) [ 42 ].…”

Modified MacConkey medium which allows simple and reliable identification of Providencia stuartii

“…This species is often not readily identified with commercial identification systems (la), notably whenever it is to be differentiated from any closely related species, i.e., Providencia rettgen and Providencia alcalifaciens. The correct identification is a clinically important goal, as P. stuartii strains show both resistance to disinfectants (5) and multiple resistance to antimicrobial drugs (2,5,6,14). Furthermore, P. stuartii may play a notable role in the spread of plasmids responsible for resistance to antimicrobial agents (21).…”