volume 1, issue 1, P100027 2020
DOI: 10.1016/j.xpro.2020.100027
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Abstract: Summary The cerebral cortex is composed of an exquisitely complex network of interconnected neurons supporting the higher cognitive functions of the brain. Here, we provide a fully detailed, step-by-step protocol to perform in utero cortical electroporation of plasmids, a simple surgical procedure designed to manipulate gene expression in a subset of glutamatergic pyramidal cortical neurons in vivo . This method has been used to visualize defects in neur…

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