In situ electrostatic assembly of porphyrin as enhanced PEC photosensitizer for bioassay of single HCT-116 cells via competitive reaction

Multiplex Signal Transduction and Output at Single Recognition Interface of Multiplexed Photoelectrochemical Sensors

“…PEC sensing, derived from electroanalysis, is a broadly used analytical method based on the principle of conversion of light into electrons. − It combines a photoelectric converter with a chemical sensing material and induces chemical reactions on the sensor surface through light irradiation to generate corresponding electrochemical signals to obtain information about the target substance. − PEC sensing technology is a significant branch of electrochemical detection, featuring real-time, fast, and simple electrochemical detection. In addition, the separation of the excitation light and detection electricity signal results in the advantages of low background signal and high detection sensitivity of PEC sensors. − Moreover, designing PEC sensor surfaces such that they interact specifically with target substances under specific reaction conditions facilitates selective detection. − This feature avoids the requirements of complex sample pretreatment and separation processes for PEC sensing technology, − highlighting the broad applicability of PEC sensing technology in the analysis of complex samples. , Notably, the detection process of PEC sensors directly involves light irradiation to produce corresponding electrochemical signals, simplifying and streamlining the operation.…”