In Situ effect of strontium toothpaste on artificially decalcified human enamel

Abstract

The aim of this study was to measure the strontium levels in surface and subsurface artificially decalcified enamel exposed in situ to a strontium-supplemented toothpaste. Twenty healthy premolar teeth extracted for orthodontic reasons were cut into blocks and demineralized. The samples were cemented to the teeth of six volunteers who brushed with a hydroxyapatite (HAP) and HAP strontium-supplemented toothpaste for 3 and 6 mo. The strontium content in the enamel surface and in the lateral wall of the enamel samples was evaluated using energy-dispersive spectrometry microanalysis. After 3 mo, the strontium content in the enamel surface increased significantly compared to baseline values. On the lateral enamel surfaces, the strontium level was the same in all of the layers after 6 mo and was higher than the level observed after 3 mo. Regular toothbrushing with a strontium-supplemented toothpaste has been found to increase the strontium content in the exposed enamel, which can be an advantage in the prevention of cariogenesis.

Bioinorganics and biomaterials: Bone repair

“…It has indeed been shown that brushing teeth with strontium-supplemented toothpastes increased the strontium content in the exposed enamel, as early as 3 weeks into treatment. This increase in strontium content is suggested to be advantageous in the treatment of cariogenesis [103].…”

Solubility of strontium-substituted apatite by solid titration

“…Consequently, a number of strontium-containing materials have been extensively used as a bone filler, such as partially strontium-substituted HAp [2][3][4][5], a-tricalcium phosphate [6] and CaSiO 3 [7], as well as strontium-containing cement [8,9]. In addition, strontium-containing toothpaste was developed to enhance the remineralization of dental enamel [10], and recently drugs such as strontium ranelate (SrR) [11] have been suggested for use as a daily supplement to increase bone mineral density.…”

High levels of heavy metal accumulation in dental calculus of smokers: a pilot inductively coupled plasma mass spectrometry study

“…On the other hand, the present study did not have any criteria about the use of toothpastes that may affect levels of Sr and Sn. Although Sr compounds are toxic to humans in high doses , they were not reported to be at toxic levels in toothpastes. Sn is reported as an element with low toxicity .…”