In Silico, In Vitro and Ex Vivo Evaluation of the Antihyperglycaemic, Antioxidant and Cytotoxic Properties of Coccinia grandis L. Leaf Extract
Pawan Prabhakar,
Sayan Mukherjee,
Ankit Kumar
et al.
Abstract:Research background. Coccinia grandis (L.) is traditionally used for the management of diabetes mellitus. Since, scientific evidence and the mechanism of action have yet to be investigated extensively, this study aimed to evaluate the antidiabetic and cytotoxic effects together with the optimization and development of a scale-up process design for higher yields of bioactive phytocompounds from C. grandis.
Experimental approach. The in silico study was performed to predict the binding affinity of phytocompound… Show more
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