Abstract:Cigarette smoke is a major risk factor in the development of Non-small cell lung cancer (NSCLC). Nicotine- derived nitrosamine ketone (NNK) is an important carcinogen present in cigarette smoke that induces tumor metastasis by activation of a protein kinase cascade, including Focal adhesion kinase (FAK). The present investigation was aimed at employing molecular docking studies to establish binding interactions and comparison of phytocomponents from different herbs and selected Rosmarinic acid derivatives agai… Show more
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