Abstract:The toxicity and high resistance to the commercially sold breast-cancer drugs have become more alarming and the demand to produce new and less toxic breast-cancer drugs arises. In silico studies was carried out on some quinoline derivatives to investigate their reported activities against breast cancer and thereby generate a model with a better activity against breast cancer. The chemical structures of the compounds were optimized using Spartan software at Density Functional Theory (DFT) level, utilizing the B… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.