In silico designed Staphylococcus aureus B-cell multi-epitope vaccine did not elicit antibodies against target antigens suggesting multi-domain approach

In Silico Analysis and Immune Response of YaeT Protein Against Riemerella anatipestifer in Ducks

“…This makes it difficult for RA protein to be used in a vaccine. Bioinformatics provides an analytical tool used to identify vaccine antigens in Staphylococcus aureus [ 28 ], E. coli [ 25 ], Burkholderia pseudomallei [ 22 ], and other pathogens [ 21 , 23 , 24 ]. Therefore, in this paper, bioinformatics tools were used to analyze the RA outer membrane protein YaeT.…”