In-room CT techniques for image-guided radiation therapy

Charlie, C.‐M.; Paskalev, K

doi:10.1016/j.meddos.2005.12.010

Cited by 96 publications

(54 citation statements)

References 32 publications

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“…Image-guided therapies often rely on real-time imaging to provide information about the tumor position. [14][15][16] The beam geometry can be updated during treatment according to the tumor motion, or gated therapy can be performed. In the case of a continuous updating process, fast image registration can be performed to track the tumor, possibly aided by fiducial markers that are implanted near the tumor.…”

Section: Introductionmentioning

confidence: 99%

Subject-specific four-dimensional liver motion modeling based on registration of dynamic MRI

et al. 2016

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Abstract. Magnetic resonance-guided high intensity focused ultrasound treatment of the liver is a promising noninvasive technique for ablation of liver lesions. For the technique to be used in clinical practice, however, the issue of liver motion needs to be addressed. A subject-specific four-dimensional liver motion model is presented that is created based on registration of dynamically acquired magnetic resonance data. This model can be used for predicting the tumor motion trajectory for treatment planning and to indicate the tumor position for treatment guidance. The performance of the model was evaluated on a dynamic scan series that was not used to build the model. The method achieved an average Dice coefficient of 0.93 between the predicted and actual liver profiles and an average vessel misalignment of 3.0 mm. The model performed robustly, with a small variation in the results per subject. The results demonstrate the potential of the model to be used for MRI-guided treatment of liver lesions. Furthermore, the model can possibly be applied in other image-guided therapies, for instance radiotherapy of the liver.

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Section: Introductionmentioning

confidence: 99%

Subject-specific four-dimensional liver motion modeling based on registration of dynamic MRI

et al. 2016

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“…They include mobile in‐room computed tomography (CT) scanners, (4) CT on rails, 5 , 6 B‐mode ultrasound systems, (6) tomotherapy, (6) and kilovoltage 7 , 8 and megavoltage 2 , 9 cone‐beam CT scanners (CBCT), widely in use currently.…”

Section: Introductionmentioning

confidence: 99%

Adaptive optimization by 6 DOF robotic couch in prostate volumetric IMRT treatment: rototranslational shift and dosimetric consequences

Chiesa

Placidi

Azario

et al. 2015

J Applied Clin Med Phys

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The purpose of this study was to investigate the magnitude and dosimetric relevance of translational and rotational shifts on IGRT prostate volumetric‐modulated arc therapy (VMAT) using Protura six degrees of freedom (DOF) Robotic Patient Positioning System. Patients with cT3aN0M0 prostate cancer, treated with VMAT simultaneous integrated boost (VMAT‐SIB), were enrolled. PTV2 was obtained adding 0.7 cm margin to seminal vesicles base (CTV2), while PTV1 adding to prostate (CTV1) 0.7 cm margin in all directions, except 1.2 cm, as caudal margin. A daily CBCT was acquired before dose delivery. The translational and rotational displacements were corrected through Protura Robotic Couch, collected and applied to the simulation CT to obtain a translated CT (tCT) and a rototranslated CT (rtCT) on which we recalculated the initial treatment plan (TP). We analyzed the correlation between dosimetric coverage, organs at risk (OAR) sparing, and translational or rotational displacements. The dosimetric impact of a rototranslational correction was calculated. From October 2012 to September 2013, a total of 263 CBCT scans from 12 patients were collected. Translational shifts were <5mm in 81% of patients and the rotational shifts were <2∘ in 93% of patient scans. The dosimetric analysis was performed on 172 CBCT scans and calculating 344 VMAT‐TP. Two significant linear correlations were observed between yaw and the V20 femoral heads and between pitch rotation and V50 rectum (p<0.001); rototranslational correction seems to impact more on PTV2 than on PTV1, especially when margins are reduced. Rotational errors are of dosimetric significance in sparing OAR and in target coverage. This is relevant for femoral heads and rectum because of major distance from isocenter, and for seminal vesicles because of irregular shape. No correlation was observed between translational and rotational errors. A study considering the intrafractional error and the deformable registration is ongoing.PACS number: 87.55.de

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“…In recent times, the cone beam computed tomography (CBCT) has been used to provide a volumetric image of the patient that is acquired just prior to treatment delivery on the treatment table. [6][7][8] Several CBCT systems are available commercially and are being used clinically in radiotherapy centres: MV CBCT, such as MVision ® , kilo voltage (kV) CBCT, such as OBI ® , XVI ® . A good imaging system needs to be safe, mechanically and geometrically accurate providing good image quality with reasonable imaging dose.…”

Section: Background and Aimmentioning

confidence: 99%

Evaluation of mechanical and geometric accuracy of two different image guidance systems in radiotherapy

Kanakavelu

Ravindran²,

Samuel

2016

Reports of Practical Oncology & Radiotherapy

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In-room CT techniques for image-guided radiation therapy

Cited by 96 publications

References 32 publications

Subject-specific four-dimensional liver motion modeling based on registration of dynamic MRI

Subject-specific four-dimensional liver motion modeling based on registration of dynamic MRI

Adaptive optimization by 6 DOF robotic couch in prostate volumetric IMRT treatment: rototranslational shift and dosimetric consequences

Evaluation of mechanical and geometric accuracy of two different image guidance systems in radiotherapy

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