In-line lead connector for use with implanted neuroprosthesis

Letechipia, Jorge; Peckham, P. Hunter; Gazdik, M.; Smith, Brian T.

doi:10.1109/10.83572

Cited by 43 publications

(32 citation statements)

References 10 publications

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“…(A) Nerve cuff electrode implanted in the forearm of subject 1. The electrode leads are connected to percutaneous leads via spring-sleeve connectors [25]. The open-helix percutaneous leads are passed individually through the skin (inset) so that the skin will grow into the open-helix, preventing pistoning of the lead and reducing the risk of bacterial infection.…”

Section: Resultsmentioning

confidence: 99%

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Stability and selectivity of a chronic, multi-contact cuff electrode for sensory stimulation in human amputees

et al. 2015

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Objective-Stability and selectivity are important when restoring long-term, functional sensory feedback in individuals with limb-loss. Our objective is to demonstrate a chronic, clinical neural stimulation system for providing selective sensory response in two upper-limb amputees.Approach-Multi-contact cuff electrodes were implanted in the median, ulnar, and radial nerves of the upper-limb.Main results-Nerve stimulation produced a selective sensory response on 19 of 20 contacts and 16 of 16 contacts in subjects 1 and 2, respectively. Stimulation elicited multiple, distinct percept areas on the phantom and residual limb. Consistent threshold, impedance, and percept areas have demonstrated that the neural interface is stable for the duration of this on-going, chronic study.Significance-We have achieved selective nerve response from multi-contact cuff electrodes by demonstrating characteristic percept areas and thresholds for each contact. Selective sensory response remains consistent in two upper-limb amputees for 1 and 2 years, the longest multicontact sensory feedback system to date. Our approach demonstrates selectivity and stability can be achieved through an extraneural interface, which can provide sensory feedback to amputees.

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Section: Resultsmentioning

confidence: 99%

“…In the mid-forearm, 8-contact FINEs were implanted around the median and ulnar nerves and a 4-contact CWRU spiral electrode was implanted around the radial nerve. Cuff leads were routed subcutaneously to percutaneous leads [22,24,25] in the upper arm ( figure 1(A)). The intraluminal size of the FINEs was 10 mm × 1.5 mm.…”

Section: Surgical Implantationmentioning

confidence: 99%

Stability and selectivity of a chronic, multi-contact cuff electrode for sensory stimulation in human amputees

et al. 2015

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“…The intramuscular electrode leads were tunneled subcutaneously and connected to an 8-channel receiverstimulator (IRS-8, not commercially available) [33] implanted in the subcutaneous fat of the lower-left quadrant of the abdomen (Figure 2). The electrode leads were connected to the IRS-8 with in-line connectors [34]. The implanted components were identical to those of the Freehand TM system, the first motor-system neuroprosthesis to receive marketing approval.…”

Section: Implanted System Implementationmentioning

confidence: 99%

Walking after incomplete spinal cord injury using an implanted FES system: A case report

Hardin¹,

Kobetic²,

Murray³

et al. 2007

JRRD

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Abstract-Implanted functional electrical stimulation (FES) systems for walking are experimentally available to individuals with incomplete spinal cord injury (SCI); however, data on short-term therapeutic and functional outcomes are limited. The goal of this study was to quantify therapeutic and functional effects of an implanted FES system for walking after incomplete cervical SCI. After robotic-assisted treadmill training and overground gait training maximized his voluntary function, an individual with incomplete SCI (American Spinal Injury Association grade C, cervical level 6-7) who could stand volitionally but not step was surgically implanted with an 8-channel receiver stimulator and intramuscular electrodes. Electrodes were implanted bilaterally, recruiting iliopsoas, vastus intermedius and lateralis, tensor fasciae latae, tibialis anterior, and peroneus longus muscles. Twelve weeks of training followed limited activity post-surgery. Customized stimulation patterns addressed gait deficits via an external control unit. The system was well-tolerated and reliable. After the 12-week training, maximal walking distance increased (from 14 m to 309 m), maximal walking speed was 10 times greater (from 0.02 m/s to 0.20 m/s), and physiological cost index was 5 times less (from 44.4 beats/m to 8.6 beats/m). Voluntary locomotor function was unchanged. The implanted FES system was welltolerated, reliable, and supplemented function, allowing the participant limited community ambulation. Physiological effort decreased and maximal walking distance increased dramatically over 12 weeks.

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“…As an illustration of a possible leakage situation, preliminary leakage tests performed in a 0.9% saline bath have shown that a 0.25mm diameter opening in the wall of a 1.57mm inner 'om LETECHIPL4 et al (1991) I I diameter (ID)/2.41 mm outer diameter (OD) silastic tube, cut with a 26 gauge hypodermic needle, will produce leakage resistance equivalent to 35 fL 4 Repair sleeve design A repair sleeve was designed to seal off current leakage paths on, or close to, an implantable in-line connector used for FES applications (LETECHIPIA et al 1991). Connectors of this design have been carefully tested (FANG and STROTHER, 1996) and have a long history of implanted use as stimulation electrode connectors.…”

Section: Effect Of Current Leakage On Implanted Sensorsmentioning

confidence: 99%