In‐house standards derived from doping peptides: Enzymatic and serum stability and degradation profile of GHRP and GHRH‐related peptides
Nicolás Mateo González‐López,
Luisa María Guerra‐Acero‐Turizo,
Isabella Blanco‐Medina
et al.
Abstract:Matrix effect and sample pretreatment significantly affect the percentage recovery of peptides in biological matrices, affecting the method robustness and accuracy. To counteract this effect, an internal standard (IS) is used; however, in most cases this is not available, which limits the analytical method. It is important to identify short peptides that can be used as ISs in the quantification of peptides in biological matrices. In this study, doping peptides GHRP‐4, GHRP‐5, GHRP‐6, Sermorelin (1 –11), Sermore… Show more
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