In-Hospital Postoperative Complications in Patients With Pituitary Adenoma Who Underwent Pituitary Surgery From January 2010 to December 2015: A Multicenter Study

Carampatana-Jandug, Claire; Esguerra, Jonis Michael; Panilagao, Gorgonia; Mejia, Athena; Rama, Jaime; Bilocura, Florenz Eubil

doi:10.14740/jem429w

Cited by 5 publications

(5 citation statements)

References 27 publications

(37 reference statements)

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“…For non-functioning macroadenomas, prompt surgical resection via a transsphenoidal approach or craniotomy is recommended in patients with visual abnormalities such as visual field defect and ophthalmoplegia [ 16 , 17 ], and more emergently in patients who present with pituitary apoplexy, loss of endocrine function, and significant tumor growth [ 15 , 18 , 28 , 44 , 45 ]. Locally, the transsphenoidal technique is the most common, which is consistent with the world standard since it can be used effectively for 95% of pituitary tumors [ 15 , 16 , 17 , 18 , 44 , 45 , 46 , 47 ]. Transcranial and endoscopic techniques are also used in more appropriate circumstances [ 15 , 16 , 17 , 18 , 44 , 45 , 46 ].…”

Section: Resultsmentioning

confidence: 99%

“…Transcranial and endoscopic techniques are also used in more appropriate circumstances [ 15 , 16 , 17 , 18 , 44 , 45 , 46 ]. Studies showed that pituitary surgery in the Philippines is relatively a safe procedure with the highest reported mortality rate of 3% and morbidity rate of 30% [ 1 , 16 , 17 ]. Local mortality and morbidity rates are higher compared to the global overall mortality rate for transsphenoidal surgery, which is less than 0.5% [ 46 ].…”

Section: Resultsmentioning

confidence: 99%

“…Locally, the transsphenoidal technique is the most common, which is consistent with the world standard since it can be used effectively for 95% of pituitary tumors [15][16][17][18][44][45][46][47]. Transcranial and endoscopic techniques are also used in more appropriate circumstances [15][16][17][18][44][45][46]. Studies showed that pituitary surgery in the Philippines is relatively a safe procedure with the highest reported mortality rate of 3% and morbidity rate of 30% [1,16,17].…”

Section: Challenges On Treatmentmentioning

confidence: 99%

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Pituitary Adenoma in the Philippines: A Scoping Review on the Treatment Gaps, Challenges, and Current State of Care

Tabuzo,

Hernandez,

Chua

et al. 2024

Medical Sciences

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Background: Pituitary adenomas are benign brain tumors that impose a heavy burden on patients worldwide. The local burden of disease is yet to be established due to scarcity of data. In line with this, this study aims to present the challenges and gaps in the treatment of pituitary adenomas in the Philippines. Methods: A scoping review of available relevant literature on epidemiology, clinical experience with treatment, health financing, and healthcare delivery system based on the Preferred Reporting Items for Systematic reviews and Meta-analysis guidelines extension for Scoping Reviews was conducted. Results: The scarcity of updated local clinical data, inequity of distribution of resources, inadequate government support, and lack of affordable diagnostic testing, medications, and neurosurgical procedures are the factors that hinder provision of adequate care of pituitary adenomas in the Philippines. Conclusion: There are notable treatment gaps in the management of pituitary adenomas in the Philippines, which may be addressed by strengthening universal healthcare. Strategies to address these gaps were proposed, including improving public-private insurance coverage, increasing manpower, enhancing accessibility to resources, and spreading more awareness.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Challenges On Treatmentmentioning

confidence: 99%

See 1 more Smart Citation

Pituitary Adenoma in the Philippines: A Scoping Review on the Treatment Gaps, Challenges, and Current State of Care

Tabuzo,

Hernandez,

Chua

et al. 2024

Medical Sciences

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“…In a multi-center, retrospective, and cohort study, Carampatana-Jandug et al, 23 reported that the most common immediate post-operative complications after pituitary surgery were DI (22.5%), followed by intracranial hemorrhage/hematoma and CSF leak. In another recent single-center retrospective review (n=22), Ugwuanyi et al, 24 reported that after surgery for pituitary adenoma, the major complications were DI (59.1%) and CSF leak (22.7%).…”

Section: Discussionmentioning

confidence: 99%

Serum sodium and water imbalance after sellar, suprasellar, and parasellar surgeries: A prospective and observational study

Das¹,

Das²,

Mandal³

et al. 2023

Asian J Med Sci

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Background: Sodium and water imbalance is common after sellar, suprasellar, and parasellar surgeries. A wide variation in the diagnostic criteria of diabetes insipidus (DI) has been noted in literature. A highly variable incidence of DI and hyponatraemia has been reported. There is paucity of Indian studies. Aims and Objectives: The study was designed to evaluate serum sodium level and water imbalance after sellar, suprasellar, and parasellar surgeries. This was evaluated in terms of occurrence of hyponatraemia and central DI on day 1 and day 7 in the post-operative period. Materials and Methods: Patients of either sex, aged from 18 to 65 years, ASA physical status I-II, GCS score ≥13, with baseline normal electrolyte level, posted for elective neurosurgical procedures for sellar, suprasellar, and parasellar tumours, were included for this study after satisfying the inclusion and exclusion criteria. A convenient sampling of 50 patients was considered for this study. The primary outcome measures were to determine the incidence of hyponatraemia and central DI. Other adverse event and any requirement of desmopressin in the post-operative period were also noted. Results: In the present study, the majority (74%) of patients were 31–50 years. Female preponderance was noted with male: female ratio as 1:1.4. Out of 50 cases 41 (82%) had transcranial surgery and 9 (18%) had transphenoidal surgery. The incidence of sodium and water disturbances (SWD) was observed in 22% (11/50) patients. Out of these 11 patients, nine developed DI and two had hyponatremia on day 1 in the post-operative period. Both the abnormalities were found to recover on day 7. Only 1 patient (2%) required desmopressin. Conclusion: The incidence of SWD after sellar, suprasellar, and parasellar surgeries was found to be common (22%). The hyponatraemia and DI responded to the therapy and were transient in nature.

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“…But, the safety and efficiency of the expanded transsphenoidal technique are still not completely recognized as there is presently inadequate clinical data. Postoperatively, Diabetes insipidus [ 25 , 26 ], visual impairment, hypopituitarism, and hypothyroidism are considered to be the most common complications [ 27 ]. These complications are mostly due to the iatrogenic injury to the connecting structures.…”

Section: Discussionmentioning

confidence: 99%

A rare case of pituicytoma-related hyperprolactinemia due to mass effect on infundibular stalk—Case report

Al-Salihi,

Ahmed,

Al-Jebur

et al. 2023

International Journal of Surgery Case Reports

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In-Hospital Postoperative Complications in Patients With Pituitary Adenoma Who Underwent Pituitary Surgery From January 2010 to December 2015: A Multicenter Study

Cited by 5 publications

References 27 publications

Pituitary Adenoma in the Philippines: A Scoping Review on the Treatment Gaps, Challenges, and Current State of Care

Pituitary Adenoma in the Philippines: A Scoping Review on the Treatment Gaps, Challenges, and Current State of Care

Serum sodium and water imbalance after sellar, suprasellar, and parasellar surgeries: A prospective and observational study

A rare case of pituicytoma-related hyperprolactinemia due to mass effect on infundibular stalk—Case report

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