In-depth evaluation of automated non-contact reflectance-based hematocrit prediction of dried blood spots

Boffel, Laura; Heughebaert, Liesl; Lambrecht, Stijn; Luginbühl, Marc; Stove, Christophe

doi:10.1039/d2an01642g

Cited by 6 publications

(1 citation statement)

References 27 publications

(67 reference statements)

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“…Instead of creating new collection devices to overcome the haematocrit effect, it is also possible to develop tools to measure the HCT of the blood spot. It can be done optically, with a smartphone app, 11 reflectance spectroscopy, 24 near‐infrared or ultraviolet‐visible spectroscopy 25 , 26 , 27 or simply with a scanner and image analysis. 28 …”

Section: Introductionmentioning

confidence: 99%

Targeted and untargeted metabolomics and lipidomics in dried blood microsampling: Recent applications and perspectives

Couacault,

Avella,

Londoño‐Osorio

et al. 2024

Analytical Science Advances

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Blood microsampling (BµS) offers an alternative to conventional methods that use plasma or serum for profiling human health, being minimally invasive and cost effective, especially beneficial for vulnerable populations. We present a non‐systematic review that offers a synopsis of the analytical methods, applications and perspectives related to dry blood microsampling in targeted and untargeted metabolomics and lipidomics research in the years 2022 and 2023. BµS shows potential in neonatal and paediatric studies, therapeutic drug monitoring, metabolite screening, biomarker research, sports supervision, clinical disorders studies and forensic toxicology. Notably, dried blood spots and volumetric absorptive microsampling options have been more extensively studied than other volumetric technologies. Therefore, we suggest that a further investigation and application of the volumetric technologies will contribute to the use of BµS as an alternative to conventional methods. Conversely, we support the idea that harmonisation of the analytical methods when using BµS would have a positive impact on its implementation.

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Section: Introductionmentioning

confidence: 99%

Targeted and untargeted metabolomics and lipidomics in dried blood microsampling: Recent applications and perspectives

Couacault,

Avella,

Londoño‐Osorio

et al. 2024

Analytical Science Advances

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Dried blood microsampling-assisted therapeutic drug monitoring of immunosuppressants: An overview

Deprez

Stove

2023

Journal of Chromatography A

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Near-infrared-based hematocrit determination of dried blood samples collected by volumetric absorptive microsampling: An in-depth evaluation

Heughebaert,

Boffel,

Lühr

et al. 2024

Microchemical Journal

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In-depth evaluation of automated non-contact reflectance-based hematocrit prediction of dried blood spots

Abstract: Dried blood spot(s) (DBS) microsampling has increasingly attracted interest as a patient-centric alternative to conventional blood withdrawal. Despite the many advantages associated with DBS sampling, its widespread use in clinical...

Cited by 6 publications

References 27 publications

Targeted and untargeted metabolomics and lipidomics in dried blood microsampling: Recent applications and perspectives

Targeted and untargeted metabolomics and lipidomics in dried blood microsampling: Recent applications and perspectives

Dried blood microsampling-assisted therapeutic drug monitoring of immunosuppressants: An overview

Near-infrared-based hematocrit determination of dried blood samples collected by volumetric absorptive microsampling: An in-depth evaluation

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