In an empirical evaluation of the funnel plot, researchers could not visually identify publication bias

Terrin, Norma; Schmid, Christopher H.; Lau, Joseph

doi:10.1016/j.jclinepi.2005.01.006

Cited by 437 publications

(336 citation statements)

References 49 publications

(72 reference statements)

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“…Statistical tests to identify this bias are unreliable in the presence of a small number of studies, as is the case with most of our outcomes. [20][21][22] Lastly, systematically searching the literature is not a standardized undertaking. We attempted to complete an inclusive search strategy and identify all relevant articles by working with an expert in library sciences.…”

Section: Discussionmentioning

confidence: 99%

“…If we perceived an outlier with a significant methodological difference that might explain the heterogeneity, we performed a sensitivity analysis excluding this outlier study. Publication bias was formally assessed with Egger's test 19 for all outcomes included in at least ten studies [20][21][22] using the comprehensive meta-analysis software, version 2.0.…”

Section: Data Extraction and Assessmentmentioning

confidence: 99%

See 1 more Smart Citation

Uterine exteriorization compared with in situ repair for Cesarean delivery: a systematic review and meta-analysis

Zaphiratos

George

Boyd

et al. 2015

Can J Anesth/J Can Anesth

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Section: Discussionmentioning

confidence: 99%

Section: Data Extraction and Assessmentmentioning

confidence: 99%

Uterine exteriorization compared with in situ repair for Cesarean delivery: a systematic review and meta-analysis

Zaphiratos

George

Boyd

et al. 2015

Can J Anesth/J Can Anesth

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“…If this is the case, the plot will have a symmetric, inverted funnel shape. If publication bias is present, the left base of the plot will disappear and the plot is asymmetric and skewed (Terrin et al, 2005). Symmetry and shape of the funnel plots were determined by means of visual inspection.…”

Section: Discussionmentioning

confidence: 99%

Staging investigations for oesophageal cancer: a meta-analysis

et al. 2008

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The aim of the study was to compare the diagnostic performance of endoscopic ultrasonography (EUS), computed tomography (CT), and 18 F-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) in staging of oesophageal cancer. PubMed was searched to identify English-language articles published before January 2006 and reporting on diagnostic performance of EUS, CT, and/or FDG-PET in oesophageal cancer patients. Articles were included if absolute numbers of true-positive, false-negative, falsepositive, and true-negative test results were available or derivable for regional, celiac, and abdominal lymph node metastases and/or distant metastases. Sensitivities and specificities were pooled using a random effects model. Summary receiver operating characteristic analysis was performed to study potential effects of study and patient characteristics. Random effects pooled sensitivities of EUS, CT, and FDG-PET for regional lymph node metastases were 0. .86 -0.96) for CT, respectively. Diagnostic performance of FDG-PET for distant metastases was significantly higher than that of CT, which was not significantly affected by study and patient characteristics. The results suggest that EUS, CT, and FDG-PET each play a distinctive role in the detection of metastases in oesophageal cancer patients. For the detection of regional lymph node metastases, EUS is most sensitive, whereas CT and FDG-PET are more specific tests. For the evaluation of distant metastases, FDG-PET has probably a higher sensitivity than CT. Its combined use could however be of clinical value, with FDG-PET detecting possible metastases and CT confirming or excluding their presence and precisely determining the location(s).

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“…This approach is based on the assumption that, in the absence of publication or availability bias, average effect size is expected to be similar in small-and large-sample studies, but vary more in smaller studies due to a greater influence of sampling error (74). Because it may be difficult to correctly identify publication bias from visual inspection of funnel plots (78), I used the funnel plot data to test for a relationship between effect size and sample size (log number of replicates) with regression analysis.…”

Section: Methodsmentioning

confidence: 99%

Effects of genotypic and phenotypic variation on establishment are important for conservation, invasion, and infection biology

Forsman

2013

Proc. Natl. Acad. Sci. U.S.A.

225

212

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There is abundant evidence that the probability of successful establishment in novel environments increases with number of individuals in founder groups and with number of repeated introductions. Theory posits that the genotypic and phenotypic variation among individuals should also be important, but few studies have examined whether founder diversity influences establishment independent of propagule pressure, nor whether the effect is model or context dependent. I summarize the results of 18 experimental studies and report on a metaanalysis that provides strong evidence that higher levels of genotypic and phenotypic diversity in founder groups increase establishment success in plants and animals. The effect of diversity is stronger in experiments carried out under natural conditions in the wild than under seminatural or standardized laboratory conditions. The realization that genetic and phenotypic variation is key to successful establishment may improve the outcome of reintroduction and translocation programs used to vitalize or restore declining and extinct populations. Founder diversity may also improve the ability of invasive species to establish and subsequently spread in environments outside of their native community, and enhance the ability of pathogens and parasites to colonize and invade the environment constituted by their hosts. It is argued that exchange of ideas, methodological approaches, and insights of the role of diversity for establishment in different contexts may further our knowledge, vitalize future research, and improve management plans in different disciplines.colonization | biological invasion | biodiversity | extinction

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In an empirical evaluation of the funnel plot, researchers could not visually identify publication bias

Cited by 437 publications

References 49 publications

Uterine exteriorization compared with in situ repair for Cesarean delivery: a systematic review and meta-analysis

Uterine exteriorization compared with in situ repair for Cesarean delivery: a systematic review and meta-analysis

Staging investigations for oesophageal cancer: a meta-analysis

Effects of genotypic and phenotypic variation on establishment are important for conservation, invasion, and infection biology

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