IMRT using simultaneous integrated boost (66 Gy in 6 weeks) with and without concurrent chemotherapy in head and neck cancer – toxicity evaluation

A Study on Conventional IMRT and RapidArc Treatment Planning Techniques for Head and Neck Cancers

“…Studies have been reported by Vosmik et al for simultaneous integrated boost and toxicity evaluation in IMRT for head and neck cancers with and without concurrent chemotherapy. 6 In this study, PTV boost consisted of the gross tumor volume and lymph nodes containing visible macroscopic tumor or biopsy-proven positive lymph nodes, whereas the PTV elective consisted of elective nodal regions. The CTV was created by manual contouring which included the GTV with a margin of 10 mm for CTV and 3 mm for PTV, respectively, which involves microscopic spread and clinically uninvolved lymph nodes and retrophargeal nodes.…”

New perspectives in radiation oncology: Young radiation oncologist point of view and challenges

“…The investigation of X-ray radiation for patient therapy moved into clinical practice in the early 1920s. 1 Since the first uses of radiation to treat cancer, important changes and advancements have occurred, [2][3][4][5] including: (1) the generation of higher energy radiation beams from linear accelerators; (2) the use of computed tomography (CT), positron emission tomography (PET), magnetic resonance (MR), and other image data sets to create three-dimensional planning models to accurately guide treatment;…”