Imputation accuracy for genomic selection using embryo biopsy samples in Gir

Oliveira, C. S.; Silva, Marcos Vinícius Gualberto Barbosa da; Quintão, C. C. R.; Otto, Pamela Itajara; Alonso, R. V.; Feres, L F; Panetto, J. C. do C.; Machado, M. A.; Camargo, Luiz Sérgio de Almeida

doi:10.1016/j.repbio.2023.100765

Cited by 3 publications

(5 citation statements)

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“…Differences of up to 875kg of milk per lactation are found between sister embryos (Mullaart and Wells, 2018). In Gir, we observed a difference of approximately 800 kg of milk per lactation between the minimum and maximum GEBV embryos on the same property (Oliveira et al, 2023). Therefore, only desirable individuals would be produced.…”

Section: Impacts Of Genomic Selection In Embryos For Brazilian Dairy ...mentioning

confidence: 79%

“…From our experience, no recommendation for call rate thresholds in Gir can be set yet, since this should consider the specific results obtained in each database. We observed a stable correlation of GEBV between embryo and calf samples across different classes of call rate samples when using Bovine HD imputation in Gir embryo biopsies ( Oliveira et al, 2023 ). A closer association between the imputed embryo samples and the reference Gir population can positively affect imputation accuracy, as is observed for imputation of young Gir bulls data ( Boison et al, 2017 ).…”

Section: Bovine Snp Chips and Imputationmentioning

confidence: 88%

“…The result is an exponential isothermal amplification of the template. After amplifying bovine embryo samples with this method, the material can be used for genotyping of SNP markers with satisfactory results ( Le Bourhis et al, 2011 ; Lauri et al, 2013 ; Oliveira et al, 2023 ).…”

Section: Whole Genome Amplificationmentioning

confidence: 99%

“…Imputation to a high-density panel such as BovineHD allows for the use of information from most SNPs detected in lower density panels. Our group conducted a study using Gir embryo biopsy genotyping with the Z-Chip panel, and found that an increased accuracy of GEBV estimates and correlation to calf samples for Bovine HD imputation compared to imputation to the Z-Chip panel ( Oliveira et al, 2023 ).…”

Section: Bovine Snp Chips and Imputationmentioning

confidence: 99%

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Embryo biopsies for genomic selection in tropical dairy cattle

et al. 2023

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Genomic selection has transformed the livestock industry, enabling early-life selection of animals. Biopsy sampling of pre-implantation embryos has been described since 1968. However, it was only after 2010, with the advancement of molecular biology techniques such as whole genomic amplification and SNP Chips, that next-generation sequencing became commercially available for bovine embryos. It is now possible to make decisions about which embryos to transfer not only based on recipients' availability or embryo morphology but also on genomic estimates. This technology can be implemented for a wide spectrum of applications in livestock. In this review, we discuss the use of embryo biopsy for genomic selection and share our experience with Gir and Girolando Brazilian breeding programs, as well as future goals for implementing it in Brazilian bovine in vitro embryo production practices.

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Section: Impacts Of Genomic Selection In Embryos For Brazilian Dairy ...mentioning

confidence: 79%

Section: Bovine Snp Chips and Imputationmentioning

confidence: 88%

Section: Whole Genome Amplificationmentioning

confidence: 99%

Section: Bovine Snp Chips and Imputationmentioning

confidence: 99%

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Embryo biopsies for genomic selection in tropical dairy cattle

et al. 2023

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“…Estudo recente mostrou que a genotipagem de embriões, seguida de análises de imputação, permitiu uma predição genômica acurada para a produção de leite em uma população de bovinos da raça Gir, com alta correção (0,87) com o GEBV estimado para os respectivos animais nascidos vivos. Isto demonstra que a seleção dos animais pode ser realizada ainda na fase embrionária, enfatizando o impacto da seleção genômica, com diminuição ainda maior do intervalo de geração e aumento do ganho genético ao longo das gerações (OLIVEIRA et al, 2023).…”

Section: Seleção Genômicaunclassified