Improving Venous Thromboembolism Prophylaxis Administration in an Acute Surgical Unit

Allaway, Matthew G R; Eslick, Guy D.; Kwok, Grace; Cox, Michael R.

doi:10.1097/pts.0000000000000521

Cited by 4 publications

(3 citation statements)

References 26 publications

(51 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…VTE is also a common and potentially fatal complication after operation. As the third leading cause of cardiovascular death, it has received more and more attention from clinicians in recent years [ 29 ], and it is also one of the common perioperative complications of urological surgery. However, SVT is more common in clinical practice and has always been regarded as a benign self-limiting disease.…”

Section: Discussionmentioning

confidence: 99%

Venous Thromboembolism and Bleeding after Transurethral Resection of the Prostate (TURP) in Patients with Preoperative Antithrombotic Therapy: A Single-Center Study from a Tertiary Hospital in China

Zheng

Liu

et al. 2023

JCM

View full text Add to dashboard Cite

Background: Venous thromboembolism (VTE) and postoperative hemorrhage are unavoidable complications of transurethral resection of the prostate (TURP). At present, more and more patients with benign prostate hyperplasia (BPH) need long-term antithrombotic therapy before operation due to cardiovascular diseases or cerebrovascular diseases. The purpose of this study was to investigate the effect of preoperative antithrombotic therapy history on lower extremity VTE and bleeding after TURP. Methods: Patients who underwent TURP in the Department of Urology, Xiangya Hospital, Central South University, from January 2017 to December 2021 and took antithrombotic drugs before operation were retrospectively analyzed. The baseline data of patients were collected, including age, prostate volume, preoperative International Prostate Symptom Score (IPSS), complications, surgical history within one month, indications of preoperative antithrombotic drugs, drug types, medication duration, etc. Main outcome measures included venous thromboembolism after TURP, intraoperative and postoperative bleeding, and perioperative blood transfusion. Secondary outcome measures included operation duration and postoperative hospitalization days, the duration of stopping antithrombotic drugs before operation, the recovery time of antithrombotic drugs after operation, the condition of lower limbs within 3 months after operation, major adverse cardiac events (MACEs), and cerebrovascular complications and death. Results: A total of 31 patients after TURP with a long preoperative history of antithrombotic drugs were included in this study. Six patients (19.4%) developed superficial venous thrombosis (SVT) postoperatively. Four of these patients progressed to deep vein thrombosis (DVT) without pulmonary thromboembolism (PE). Only one patient underwent extra bladder irrigation due to blockage of their urinary catheter by a blood clot postoperatively. The symptoms of hematuria mostly disappeared within one month postoperatively and lasted for up to three months postoperatively. No blood transfusion, surgical intervention to stop bleeding, lower limb discomfort such as swelling, MACEs, cerebrovascular complications, or death occurred in all patients within three months after surgery. Conclusion: Short-term preoperative discontinuation may help patients with antithrombotic therapy to obtain a relatively safe opportunity for TURP surgery after professional evaluation of perioperative conditions. The risks of perioperative bleeding, VTE, and serious cardiovascular and cerebrovascular complications are relatively controllable. It is essential for urologists to pay more attention to the perioperative management of these patients. However, further high-quality research results are needed for more powerful verification.

show abstract

Section: Discussionmentioning

confidence: 99%

Venous Thromboembolism and Bleeding after Transurethral Resection of the Prostate (TURP) in Patients with Preoperative Antithrombotic Therapy: A Single-Center Study from a Tertiary Hospital in China

Zheng

Liu

et al. 2023

JCM

View full text Add to dashboard Cite

show abstract

“…Patients with post-appendicectomy IAA were identified as part of a large cases series study on the outcomes of appendicectomy. 8,30,31 Prior to commencement of the study, ethics approval was obtained from the Nepean Blue Mountains Local Health District Human Research Ethics Committee (study numbers 14/29 and 14/67). Only patients with suspected acute appendicitis were included; appendicectomies performed for other indications were excluded.…”

Section: Methodsmentioning

confidence: 99%

“…A retrospective case note review was performed for post‐appendicectomy IAA from 2006 to 2017 at Nepean Hospital, Western Sydney, Australia. Patients with post‐appendicectomy IAA were identified as part of a large cases series study on the outcomes of appendicectomy 8,30,31 . Prior to commencement of the study, ethics approval was obtained from the Nepean Blue Mountains Local Health District Human Research Ethics Committee (study numbers 14/29 and 14/67).…”

Section: Methodsmentioning

confidence: 99%

Non‐operative management of small post‐appendicectomy intra‐abdominal abscess is safe and effective

Collins

Allaway

Eslick

et al. 2020

ANZ Journal of Surgery

Self Cite

View full text Add to dashboard Cite

Background: Intra-abdominal abscess (IAA) post-appendicectomy occurs in 1.4-4.4% of cases. Non-operative management of small (<4 cm) post-appendicectomy IAA in children is well established, but minimal evidence exists in adults. Percutaneous catheter drainage is considered standard treatment for IAA, yet outcome data for post-appendicectomy IAA are sparse. The aims of this study were to assess the effectiveness of non-operative management of small (<4 cm diameter) IAA and the outcomes of percutaneous drainage for larger (>4 cm) IAA post-appendicectomy. Methods: A retrospective case note review of a series of patients with a postappendicectomy IAA between 2006 and 2017 was conducted. IAAs were treated selectively; small (<4 cm) IAAs were managed non-operatively and larger IAAs were managed with percutaneous drainage. Results: A total of 4901 patients had an appendicectomy. Forty-two (0.9%) developed a post-operative IAA. Sixteen (38%) had a percutaneous drainage and 26 (62%) had non-operative management. The percutaneous drainage group had a higher proportion of complicated appendicitis (75%) compared to the non-operative group (42%, P = 0.04). The percutaneous drainage group had a significantly higher leucocytosis (P = 0.01) and C-reactive protein (P = 0.02). All patients managed non-operatively resolved without the need for invasive procedures. In the percutaneous drainage group, six had aspiration alone, nine had a percutaneous drain and one was abandoned. Three required repeat percutaneous drainage and four (25%) required operative drainage. Seven patients (34%) of the percutaneous drainage group had grade II or III complications. Conclusion: This case series study provides support that small (<4 cm) IAA postappendicectomy can be safely and effectively managed non-operatively.

show abstract

Achieving durable compliance with venous thromboembolism prophylaxis in bariatric surgery: 3-year data from a major academic medical center

Mou,

Falconer,

Majumdar

et al. 2024

Surgery for Obesity and Related Diseases

View full text Add to dashboard Cite

Improving Venous Thromboembolism Prophylaxis Administration in an Acute Surgical Unit

Cited by 4 publications

References 26 publications

Venous Thromboembolism and Bleeding after Transurethral Resection of the Prostate (TURP) in Patients with Preoperative Antithrombotic Therapy: A Single-Center Study from a Tertiary Hospital in China

Venous Thromboembolism and Bleeding after Transurethral Resection of the Prostate (TURP) in Patients with Preoperative Antithrombotic Therapy: A Single-Center Study from a Tertiary Hospital in China

Non‐operative management of small post‐appendicectomy intra‐abdominal abscess is safe and effective

Achieving durable compliance with venous thromboembolism prophylaxis in bariatric surgery: 3-year data from a major academic medical center

Contact Info

Product

Resources

About