Improving transient elastography performance for detecting hepatitis B cirrhosis

Diagnostic accuracy of two-dimensional shear wave elastography for the non-invasive staging of hepatic fibrosis in chronic hepatitis B: a cohort study with internal validation

“…Transient elastography (TE), point shear-wave elastography (pSWE) and two-dimensional shear wave elastography (2D-SWE) can calculate the speed of shear waves, which is directly related to tissue stiffness [6]. TE is the oldest and most validated elastographic method for assessing liver fibrosis [7][8][9][10][11]. TE has been recommended for noninvasively staging hepatic fibrosis in the clinical practice guidelines of the European Association for the Study of the Liver [12].…”

Non‐invasive assessment of liver fibrosis: reduce or substitute the need for liver biopsy?

“…Thus, to minimize false diagnosis, optimal cut-offs determination should refer to likelihood ratio, 95% sensitivity and 95% specificity. Compared with nearly 80% accuracy by single cut-off in this article, diagnostic accuracy by dual cut-offs were over 92%, with nearly 30% of patients needing liver biopsy (4,5).…”

Consensus on the diagnosis and treatment of hepatic fibrosis (2019)

“…The diagnostic cut‐off value should be referred to the etiology and serum ALT level and exclude the possibility of right heart failure . Table shows the diagnostic value of LSM in patients with chronic hepatitis B and C …”