Improving the feeder shoe design of an eccentric tablet press machine

Ramírez-Aragón, Cristina; Alba‐Elías, Fernando; Marcos, Ana González; Ordieres-Meré, Joaquín

doi:10.1016/j.powtec.2020.05.104

Cited by 3 publications

(2 citation statements)

References 34 publications

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“…Segregation was observed in the shoe itself upon filling even before the movement sequence started. Nevertheless, the study demonstrated that the shoe design configuration can be optimized with the help of DEM modeling, and proper inserts, the aim of which is to reduce friction at the shoe bottom or to increase the confinement and immobilize the material at the top section, are able to cut the segregation index even by up to 50% [63].…”

Section: Studies On Segregation In Stationary Die and Moving Shoementioning

confidence: 99%

Blend Segregation in Tablets Manufacturing and Its Effect on Drug Content Uniformity—A Review

Jakubowska

Ciepluch

2021

Pharmaceutics

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Content uniformity (CU) of the active pharmaceutical ingredient is a critical quality attribute of tablets as a dosage form, ensuring reproducible drug potency. Failure to meet the accepted uniformity in the final product may be caused either by suboptimal mixing and insufficient initial blend homogeneity, or may result from further particle segregation during storage, transfer or the compression process itself. This review presents the most relevant powder segregation mechanisms in tablet manufacturing and summarizes the currently available, up-to-date research on segregation and uniformity loss at the various stages of production process—the blend transfer from the bulk container to the tablet press, filling and discharge from the feeding hopper, as well as die filling. Formulation and processing factors affecting the occurrence of segregation and tablets’ CU are reviewed and recommendations for minimizing the risk of content uniformity failure in tablets are considered herein, including the perspective of continuous manufacturing.

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Section: Studies On Segregation In Stationary Die and Moving Shoementioning

confidence: 99%

Blend Segregation in Tablets Manufacturing and Its Effect on Drug Content Uniformity—A Review

Jakubowska

Ciepluch

2021

Pharmaceutics

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“…The initial method used was a direct visit to the tofu factory in the district. Subang and conducted interviews with the tofu makers, the results of the interviews conducted at the tofu factory were the lack of awareness about the maintenance of the tools used, especially the tofu presses [12], so that periodic maintenance of the tofu presses was necessary.…”

Section: Observationmentioning

confidence: 99%

Maintenance of Pressing and Touch Cutting Equipment with the Pneumatic System of Subang State Polytechnic

Efendi,

Ihsan,

Nugroho

et al. 2021

VANOS JMEE

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This study aims to make a preventive maintenance plan for tofu presses and cutters with a pneumatic system with the methods carried out namely inspection, small repair, medium repair and overhaul (ISMO). The preventive maintenance time on presses and tofu cutters with this pneumatic system is carried out with this type of maintenance on a monthly and annual basis. The research stages of implementing preventive maintenance on tofu presses and cutters with a pneumatic system includes literature studies, making maintenance schedules and expert validation. Components carried out preventive maintenance on the mechanical system which includes the frame, drive system, compressor and blades. data collection using observation and documentation. data were analyzed descriptively quantitative. The results showed that the preventive maintenance of tofu presses and cutters with a pneumatic system was intended to maintain the condition of the tools as well as to extend their service life and streamline the production process.

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Recent progress on the discrete element method simulations for powder transport systems: A review

Shi

Sakai

2022

Advanced Powder Technology

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Improving the feeder shoe design of an eccentric tablet press machine

Cited by 3 publications

References 34 publications

Blend Segregation in Tablets Manufacturing and Its Effect on Drug Content Uniformity—A Review

Blend Segregation in Tablets Manufacturing and Its Effect on Drug Content Uniformity—A Review

Maintenance of Pressing and Touch Cutting Equipment with the Pneumatic System of Subang State Polytechnic

Recent progress on the discrete element method simulations for powder transport systems: A review

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