“…The inherent limits of low-risk thresholds are quite obvious and should be acknowledged – certainly so when used in a healthcare setting. Here, we are not only thinking about the fact that guideline panels make quite arbitrary cut-offs on smooth risk curves ( Room & Rehm, 2012 ), or that the 1‰ or 1% risk levels are far from given ( Livingston, 2023 ). We, as others, also believe that any guideline should allow people to make decisions based on their own risk tolerance ( Livingston, 2023 ).…”