Improving the Chromatographic Analysis
of N-Nitrosamines in Drinking Water
by Completely Drying the Solid Sorbent
Using Dry Air

Jung, Sungjin; Kim, Dasom; Kim, Hekap

doi:10.15244/pjoes/64311

Cited by 5 publications

(2 citation statements)

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“…The analytical method used in this study was an improved modification of those in previous reports in which dry air was not used to remove water from the cartridge [6,25,26], and secondary amines, including DMA, were not removed prior to chemical derivatization [22]. Optimizations were carried out to dry the sorbent cartridge, select the extracting solvents, and remove secondary amines.…”

Section: Optimization Of the Analytical Methods For Ndma In Watermentioning

confidence: 99%

“…This value is~1000 times greater than those of bromodichloromethane (1.8 × 10 −6 per µg/L) [4] and dichloroacetic acid (1.4 × 10 −6 per µg/L) [5], which are frequently found at µg/L levels in chlorinated drinking water. However, NDEA has been found When HPLC coupled with fluorescence detection (FLD) is used to determine NAs, including NDMA, they are most frequently converted to fluorescent 5-dimethylamino-1-naphthalenesulfonyl (dansyl) derivatives [22,[27][28][29]. However, this method requires the removal of residual secondary amines, including DMA, which are organic precursors to NAs from the eluate prior to derivatization, because drinking water typically contains a few µg/L levels of secondary amines [9,30,31].…”

Section: Introductionmentioning

confidence: 99%

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Regional and Seasonal Distributions of N-Nitrosodimethylamine (NDMA) Concentrations in Chlorinated Drinking Water Distribution Systems in Korea

Park

Jung

Kim

2019

Water

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Volatile N-Nitrosamines (NAs), including N-nitrosodimethylamine (NDMA), an emerging contaminant in drinking water, have been reported to induce cancer in animal studies. This study aims to investigate the regional and seasonal distributions of the concentrations of NDMA, one of the most commonly found NAs with high carcinogenicity, in municipal tap water in Korea. NDMA in water samples was quantitatively determined using high-performance liquid chromatography-fluorescence detection (HPLC-FLD) as a 5-dimethylamino-1-naphthalenesulfonyl (dansyl) derivative after optimization to dry the SPE adsorbent and remove dimethylamine prior to derivatization. Tap water samples were collected from 41 sites in Korea, each of which was visited once in summer and once in winter. The average (±standard deviation) NDMA concentration among all the sites was 46.6 (±22.7) ng/L, ranging from <0.13 to 80.7 ng/L. Significant NDMA differences in the regions, excluding the Jeju region, were not found, whereas the average NDMA concentration was statistically higher in winter than in summer. A multiple regression analysis for the entire data set indicated a negative relationship between NDMA concentration and water temperature. High levels of NDMA in Korea may pose excessive cancer risks from the consumption of such drinking water.

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Section: Optimization Of the Analytical Methods For Ndma In Watermentioning

confidence: 99%