Improving the bioavailability of manganese and meat quality of broilers by using hot-melt extrusion nano method

Kim, M J; Hosseindoust, Abdolreza; Kim, K Y; Moturi, Joseph; Lee, J H; Kim, T G; Mun, Jun Young; Chae, B. J.

doi:10.1080/00071668.2021.1955332

Cited by 3 publications

(2 citation statements)

References 30 publications

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“…Dulbecco's modified Eagle's medium (DMEM), penicillin-streptomycin, and fetal bovine serum (FBS) were obtained from Gibco Life Technologies, Inc. (Grand Island, NY, USA). [8][9][10]16]. Those blended materials were translocated to the hopper part of HME (45 g/min rate).…”

Section: Methodsmentioning

confidence: 99%

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Manganese Sulfate Nanocomposites Fabricated by Hot-Melt Extrusion for Chemodynamic Therapy of Colorectal Cancer

et al. 2023

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The development of metal salts-based nanocomposites is highly desired for the Fenton or Fenton-like reaction-based chemodynamic therapy of cancer. Manganese sulfate (MnSO4)-dispersed nanoparticles (NPs) were fabricated with a hot-melt extrusion (HME) system for the chemodynamic therapy of colorectal cancer in this study. MnSO4 was homogeneously distributed in polyethylene glycol (PEG) 6000 (as a hydrophilic polymer) with the aid of surfactants (Span 80 and Tween 80) by HME processing. Nano-size distribution was achieved after dispersing the pulverized extrudate of MnSO4-based composite in the aqueous media. The distribution of MnSO4 in HME extrudate and the interactions between MnSO4 and pharmaceutical additives were elucidated by Fourier-transform infrared, X-ray diffractometry, X-ray photoelectron spectroscopy, and scanning electron microscopy analyses. Hydroxyl radical generation efficiency by the Fenton-like chemistry capability of Mn2+ ion was also confirmed by catalytic assays. By using the intrinsic H2O2 in cancer cells, MnSO4 NPs provided an elevated cellular reactive oxygen species level, apoptosis induction capability, and antiproliferation efficiency. The designed HME-processed MnSO4 formulation can be efficiently used for the chemodynamic therapy of colorectal cancer.

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Section: Methodsmentioning

confidence: 99%

“…MnSO 4 , PEG 6000, Span 80, and Tween 80 were blended at a 20:64:12:4 ratio ( w / w / w / w ) prior to putting those materials into the extruder [ 8 , 9 , 10 , 16 ]. Those blended materials were translocated to the hopper part of HME (45 g/min rate).…”

Section: Methodsmentioning

confidence: 99%

Manganese Sulfate Nanocomposites Fabricated by Hot-Melt Extrusion for Chemodynamic Therapy of Colorectal Cancer

et al. 2023

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Effect of manganese amino acid complexes on growth performance, meat quality, breast muscle and bone development in broilers

Li,

Ma,

Zuo

et al. 2024

British Poultry Science

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Use of Additives and Evaluation of the Quality of Broiler Meat

Soares¹,

Silva²

2022

Broiler Industry

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In the poultry industry, the demand for safe and quality meat in the market has increased considerably. The type of feed used and the management of poultry have a significant impact on the safety and quality characteristics of poultry meat. The use of additives that increase productivity and improve meat quality has generated much research. Nanoparticles, prebiotics, and probiotics have been used as growth promoters to increase and improve growth rate, performance, immunity, resistance to pathogens, as well as to improve meat quality. The type and level of these additives incorporated in the diets influence the animal’s development and meat quality parameters. The aim of the study was to report the results of scientific research on the use of food additives used in broiler nutrition and their effect on meat quality.

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Improving the bioavailability of manganese and meat quality of broilers by using hot-melt extrusion nano method

Cited by 3 publications

References 30 publications

Manganese Sulfate Nanocomposites Fabricated by Hot-Melt Extrusion for Chemodynamic Therapy of Colorectal Cancer

Manganese Sulfate Nanocomposites Fabricated by Hot-Melt Extrusion for Chemodynamic Therapy of Colorectal Cancer

Effect of manganese amino acid complexes on growth performance, meat quality, breast muscle and bone development in broilers

Use of Additives and Evaluation of the Quality of Broiler Meat

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