Improving SERS biosensors for the analysis of ovarian cancer-derived small extracellular vesicles

Ngo, Long; Zhang, Wei; Hnit, Su Su Thae; Wang, Yuling

doi:10.1039/d3an00398a

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Development Of Platform Technologies For Sers-based Bioassays1

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2024

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Cited by 9 publications

(1 citation statement)

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“…However, further research is required to assess SERS spectroscopy sensitivity and specificity for bioassays and optimize the technique for practical use in clinical settings. Additionally, 2D materials 52–58 and magnetic materials 59–74 have been introduced as efficient SERS nanotags (Fig. 2).…”

Section: Development Of Platform Technologies For Sers-based Bioassaysmentioning

confidence: 99%

SERS-based microdevices for use as in vitro diagnostic biosensors

Lee,

Dang,

Moon

et al. 2024

Chem. Soc. Rev.

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Section: Development Of Platform Technologies For Sers-based Bioassaysmentioning

confidence: 99%

SERS-based microdevices for use as in vitro diagnostic biosensors

Lee,

Dang,

Moon

et al. 2024

Chem. Soc. Rev.

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Extracellular Vesicle Preparation and Analysis: A State‐of‐the‐Art Review

Wang,

Zhou,

Kong

et al. 2024

Advanced Science

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In recent decades, research on Extracellular Vesicles (EVs) has gained prominence in the life sciences due to their critical roles in both health and disease states, offering promising applications in disease diagnosis, drug delivery, and therapy. However, their inherent heterogeneity and complex origins pose significant challenges to their preparation, analysis, and subsequent clinical application. This review is structured to provide an overview of the biogenesis, composition, and various sources of EVs, thereby laying the groundwork for a detailed discussion of contemporary techniques for their preparation and analysis. Particular focus is given to state‐of‐the‐art technologies that employ both microfluidic and non‐microfluidic platforms for EV processing. Furthermore, this discourse extends into innovative approaches that incorporate artificial intelligence and cutting‐edge electrochemical sensors, with a particular emphasis on single EV analysis. This review proposes current challenges and outlines prospective avenues for future research. The objective is to motivate researchers to innovate and expand methods for the preparation and analysis of EVs, fully unlocking their biomedical potential.

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