Improving safety of preparation and administration of medicines and enteral nutrition in a neonatal care unit: Global risk analysis

Zribi, Kaouther; Seydoux, C.L.; Coatantiec, Y.; Chenet, Veronique; Karnycheff, F.; Sejean, Karine; Vivet, A.; Migeon, A.; Aboulghit, K.; Ayoubi, Jean Marc; Bonan, Brigitte

doi:10.1016/j.pharma.2019.12.005

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…In premature infants, the incidence rate between the intervention group and the control group is more significant than that of the term infant group; in many systems, the incidence rate has been significantly reduced, and more system diseases showed statistical differences [ 11 ]. For example, there are significant differences in bradycardia (heart rate <100 beats/min), Apgar <7 points in 1 minute or 5 minutes after admission, and there are statistically significant differences ( P < 0.05); at the same time in the respiratory system, the incidence of oxygen demand, neonatal wet lung, and apnea in the intervention group was significantly reduced, and there were statistical differences ( P < 0.05); although aspiration pneumonia, RDS, and respiratory failure showed a downward trend in this group of studies, there was no statistical difference ( P > 0.05).…”

Section: Results Analysismentioning

confidence: 99%

Research on the Application Value of Intelligent Heating Box in Newborn Nursing

2021

Contrast Media & Molecular Imaging

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The aim of this study was to explore the application effect of intelligent incubator in neonatal care. We selected the period from January 1, 2018, to December 31, 2020, where there were 100 full-term and premature babies born in a hospital and transferred to the neonatal intensive care unit (NICU) within 1 hour after birth. Before the improved heat preservation, 100 full-term infants in the control group and 100 full-term infants in the intervention group of the intelligent warming box were formed into a full-term infant group for a comparative study. Statistics and comparison of the two groups of term infants and premature infants admitted to the hospital were carried out to assess body temperature and the changes in the incidence of each system. The research found that on comparison of admission body temperature between the control group and the intervention group, with the intervention group in the intelligent heating box, the incidence of hypothermia was significantly lower than that of the control group (95% vs. 37% of full-term infants; 98% vs. 49% of premature babies; there is a statistical significance ( P < 0.05 )). The intelligent heating box can reduce the fluctuation of the newborn’s body temperature, keep the internal environment of newborns stable, and provide suitable conditions for the rapid growth of newborns, suitable for clinical promotion and application.

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Section: Results Analysismentioning

confidence: 99%

Research on the Application Value of Intelligent Heating Box in Newborn Nursing

2021

Contrast Media & Molecular Imaging

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“…Pre-existing risk analyses have been performed in the area of health care, but data in the literature on contracting out centralized injectable preparations are scarce. [15][16][17][18][19][20][21] Therefore, it was difficult to compare with other studies to improve our GRA. The implementation of the GRA requires significant time and effort.…”

Section: Study Limitsmentioning

confidence: 99%

Subcontracting sterile pediatric and adult chemotherapy preparations activity: A global risk analysis

Rousseau

Zribi

Cotteret

et al. 2022

Health Science Reports

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Objective The main purpose of this study was to carry out a global risk analysis (GRA) on the subcontracting circuit to determine and evaluate the risks linked to the future subcontracting process and to propose corrective actions for the most critical risks to ensure safety. This study must allow to conclude in an objective way to the feasibility or not of this project. Methods A GRA was performed, conducted by a multidisciplinary working group that met in 20 meetings, corresponding to about 50 h of work. Results We identified 92 scenarios: 13% of scenarios had an initial criticality C1, 40% C2, and 47% C3. The GRA shows that the riskiest scenarios concern the management, material, and equipment with IT system and logistics with transport. The working group identified 25 corrective actions. After implementing those actions, 85% of scenarios had residual criticality C1, 8.5% C2, and 6.5% had residual criticality C3. The working group chose that it was impossible to subcontract part of the activity. Conclusion The GRA conducted in this study highlighted the risks related to outsourcing this activity, evaluated and prioritized them, and recommended corrective actions. Therefore, we conclude that subcontracting the totality of sterile preparations would be harmful to patient care quality and reactivity for vital medical emergencies, such as macrophage activation syndrome, preparation of clinical trials, graft rejection therapies, preparation of very short stability chemotherapy, and the pediatric graft conditioning chemotherapy.

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Improving safety of preparation and administration of medicines and enteral nutrition in a neonatal care unit: Global risk analysis

Cited by 2 publications

References 14 publications

Research on the Application Value of Intelligent Heating Box in Newborn Nursing

Research on the Application Value of Intelligent Heating Box in Newborn Nursing

Subcontracting sterile pediatric and adult chemotherapy preparations activity: A global risk analysis

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