Improving outcomes in cancer diagnosis, prevention and control: barriers, facilitators and the need for health literacy in Ibadan Nigeria

Adedimeji, Adebola; Lounsbury, David W.; Popoola, Oluwafemi; Asuzu, Chioma; Lawal, Akinmayowa; Oladoyin, Victoria; Crifase, Cassandra; Agalliu, Ilir; Shankar, Viswanathan; Adebiyi, Akindele Olupelumi

doi:10.1002/pon.4158

Cited by 12 publications

(7 citation statements)

References 29 publications

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“…Improvements in survival may be possible with promotion of early presentation through outreach and education programs teaching providers in rural areas about the signs and symptoms of cancer. Several such efforts are being piloted in Africa aiming to reduce delayed presentation . Our data did not show a high rate of treatment‐related mortality, with most known causes of death related to tumor.…”

Section: Discussionmentioning

confidence: 52%

Survival of children with endemic Burkitt lymphoma in a prospective clinical care project in Uganda

McGoldrick

Mutyaba

Adams

et al. 2019

Pediatric Blood & Cancer

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Purpose “Endemic” Burkitt lymphoma (BL) is a common childhood cancer in Africa. Social and treatment factors may contribute to poor survival. With the aim of improving BL outcomes in Uganda, we undertook a comprehensive project (BL Project) that provided diagnostic support, access to standard chemotherapy, nutritional evaluations, and case management. We evaluated survival of children with BL in the context of the project. Patients and methods Patients followed by the BL Project who consented to research were enrolled in this study. Children with a pathology diagnosis consistent with BL were eligible. Data were collected prospectively. First‐line chemotherapy generally consisted of six cycles of cyclophosphamide, vincristine, low‐dose methotrexate (COM). We used Kaplan–Meier and Cox regression analyses to evaluate factors associated with overall survival (OS). Results Between July 2012 and June 2017, 341 patients with suspected BL presented to the BL Project. One hundred eighty patients with a pathology‐based diagnosis were included in this study. The median age was seven years (interquartile range, 5–9), 74% lived ≥100 km from the Uganda Cancer Institute, 61% had late‐stage disease, 84% had ECOG performance status < 3, 63% reported B‐symptoms, and 22% showed neurologic symptoms. Fewer than 10% abandoned therapy. The four‐year OS rate was 44% (95% CI, 36%–53%). In a multivariate model, ECOG status was significantly associated with mortality. Conclusion The BL Project reduced effects of lacking supportive care and oncology resources, and allowed patients from Uganda to receive curative intent therapy with minimal loss to follow‐up. Nonetheless, OS remains unacceptably low. Improved therapeutic approaches to endemic BL are urgently needed in Africa.

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Section: Discussionmentioning

confidence: 52%

Survival of children with endemic Burkitt lymphoma in a prospective clinical care project in Uganda

McGoldrick

Mutyaba

Adams

et al. 2019

Pediatric Blood & Cancer

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“…The myths about hypertension are of serious concern. Similar myths and misconceptions were identified in the studies on hypertension and breast cancer in Nigeria [13] [24]. There is a need for awareness programme to address misconceptions.…”

Section: Resultsmentioning

confidence: 65%

Perceptions and Thirst for Knowledge Regarding Hypertension among Rural Dwellers in Isunjaba, Imo State, Nigeria: A Qualitative Study

Osuala¹,

Oluwatosin²,

Osuala³

et al. 2016

Health

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Hypertension accounts for 13% of global mortality, is one of the most frequent causes of end stage kidney failure in the world, and has a 25% prevalence in Nigeria. Primary prevention based on comprehensive population-based intervention has been found most economical. Lifestyle modification is an essential part of management. It is important for the researcher to have a deep understanding of people's perceptions and attitudes to diseases like hypertension where effective interventions must address lifestyle choices of community members. Thus, this descriptive qualitative study carried out among 48 rural dwellers between ages 20 and 75 in Isunjaba, Imo state, to determine their perception and attitude to hypertension issues. Information gathered would be used in creating intervention programme to prevent hypertension and promote health. Findings revealed that participants were aware of incidents of sudden deaths and stroke in the town. There was a strong belief among members that hypertension "can be sent by one's enemy", even though majority attributed it to "worries and much thinking". Unhealthy lifestyles such as alcohol, and stimulant consumption (kolanut and snuff) were elicited. Daily activities were said to be equivalent to regular exercise. Participants were eager for measures to prevent hypertension and curb the incidence of stroke in the communities. There is therefore the need to institute hypertension awareness and blood pressure monitoring programme in the community.

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“…To date, however, there has only been one study on this topic in Nigeria. In that study, high morbidity and mortality associated with cancer were partly due to low health literacy (Adedimeji et al, 2017). Giving attention to health literacy assessment and promotion may assist in early detection and better care trajectory (Adedimeji et al, 2017).…”

Section: Introductionmentioning

confidence: 94%

Quality of life and associated factors among adults living with cancer and their family caregivers

Gabriel

Creedy

Coyne

2021

Nursing & Health Sciences

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This study examined the association of needs, health literacy, and quality of life among adult Nigerians with cancer and family caregivers. A descriptive study was conducted involving 240 adults with cancer and family caregivers attending a tertiary hospital. More than two‐thirds of participants reported moderate or high needs. Information (90.8%) and spiritual support (85%) were the domains of highest need among adults with cancer. Family/social support (85%) and spiritual support (81.7%) ranked the highest among family caregivers. A negative correlation was found between needs and quality of life. Stepwise regression analysis showed that needs and literacy explained 36% of the variance in adults with cancer's quality of life and 28% of the variance in family caregivers’ quality of life. Spiritual need accounted l for 9.5% and 9.1% of variation for adults with cancer and family caregivers, respectively. Findings suggest that interventions with a focus on social/family and spiritual needs may improve wellbeing of adults with cancer and caregivers in Nigeria. This research are generalizable to other low‐income countries where family values and spirituality are often a strong feature of daily life.

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Improving outcomes in cancer diagnosis, prevention and control: barriers, facilitators and the need for health literacy in Ibadan Nigeria

Abstract: Developing and implementing comprehensive context-relevant health literacy interventions in community settings are urgently needed.Copyright © 2016 John Wiley & Sons, Ltd.

Cited by 12 publications

References 29 publications

Survival of children with endemic Burkitt lymphoma in a prospective clinical care project in Uganda

Survival of children with endemic Burkitt lymphoma in a prospective clinical care project in Uganda

Perceptions and Thirst for Knowledge Regarding Hypertension among Rural Dwellers in Isunjaba, Imo State, Nigeria: A Qualitative Study

Quality of life and associated factors among adults living with cancer and their family caregivers

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