Improving nutritional screening of hospitalized patients: the role of prealbumin

Robinson, Malcolm K.; Trujillo, Elaine B.; Mogensen, Kris M.; Rounds, Jan D.; McManus, Katherine; Jacobs, Danny O.

doi:10.1177/0148607103027006389

Cited by 102 publications

(65 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, its function in nutritional screening and in predicting mortality is controversial (Ferguson et al, 1993;Brugler et al, 2002;Langkamp-Henken et al, 2005;Devoto et al, 2006;Carriere et al, 2008). Robinson et al (2003) found prealbumin to be a significant predictor of malnutrition, whereas serum albumin and retinol-binding protein were not. Retinol-binding protein behaves similarly to prealbumin, but has an even shorter half-life (6-12 h).…”

Section: Discussionmentioning

confidence: 99%

Comparison of two malnutrition risk screening methods (MNA and NRS 2002) and their association with markers of protein malnutrition in geriatric hospitalized patients

et al. 2010

View full text Add to dashboard Cite

Background: Malnutrition occurs frequently in the elderly and is associated with increased morbidity and mortality. The mininutritional assessment (MNA) has been used most frequently in the geriatric literature. The nutritional risk screening 2002 (NRS) has been proposed as universal screening method for hospitalized patients. The aim of our study was to compare both tools as they are correlated with protein malnutrition. Methods: MNA, NRS, and markers of protein malnutrition were measured in 104 consecutive inpatients admitted to an acute geriatric ward. Results: The median age was 84 years (IQR: 78-89), 81 were females. The median body mass index was 23.1 kg/m 2 (IQR: 20-27.3), the median upper-arm and calf circumferences were 25 cm (IQR: 23-29) and 33 cm (IQR: 29-36). According to MNA, 23 patients were malnourished, 50 at risk of malnutrition, and 31 had a normal nutritional status. The NRS indicated that 35 were at moderate to severe risk of malnutrition and 69 at low risk. Serum prealbumin and retinol-binding protein concentrations were inversely associated with the severity of malnutrition as indicated by the NRS (P ¼ 0.06 and o0.01, respectively), whereas the MNA was not associated with these serum proteins. After adjustment for C-reactive protein and creatinine clearance, only retinol-binding protein concentrations were consistently associated with both malnutrition scores. Conclusions: The NRS seems to be superior compared with the MNA and serum proteins in identifying elderly patients at risk of malnutrition during acute intercurrent illness.

show abstract

Section: Discussionmentioning

confidence: 99%

Comparison of two malnutrition risk screening methods (MNA and NRS 2002) and their association with markers of protein malnutrition in geriatric hospitalized patients

et al. 2010

View full text Add to dashboard Cite

show abstract

“…On the other hand, the independent relationship between outcomes and also the single components of NRS-2002 have been recently associated with outcome [5]. This does not mean that the choice of analytical criteria should be preferred to that of simple and widely applicable validated tools, because the latter (albumin, prealbumin, weight loss and reduced food intake) can account for the effect of disease on nutritional risk only in part [30][31][32][33]. Our choice was not random and reflects all the efforts that should be made to identify, and so to treat, every patient at risk.…”

Section: Discussionmentioning

confidence: 99%

A nationally representative survey of hospital malnutrition: the Italian PIMAI (Project: Iatrogenic MAlnutrition in Italy) study

Lucchin

D'Amicis

Gentile

et al. 2009

Mediterr J Nutr Metab

View full text Add to dashboard Cite

*See the end of the text for the complete list of affiliations Overall prevalence of malnutrition was 30.7%, with higher rates in the northern macroarea (36.7%) than in central (28.0%), southern (26.9%) and island (16.7%) ones (p < 0.0001). This discrepancy appeared to be mainly related to the prevalence of overweight/obesity. By a multivariate model, malnutrition was significantly lower in males (p < 0.05) and surgical wards (p < 0.002), associated with geography (p < 0.05) and consistently higher in patients aged ≥65 years (p < 0.01), presenting with malignancies (p < 0.005) and having multidrug therapy (p < 0.05). The prevalence of hospital malnutrition is high also in Italy. It presents with different geographical distribution also according to overweight prevalence. This evidence should be considered when designing national nutritional policies.

show abstract

“…This type of classification, however, may often reflect severity of illness and the magnitude of the SIRS rather than nutritional status. When screening protocols that use prealbumin have been compared with a 2-stage process involving a screening questionnaire followed by an assessment by a professional dietitian, the prealbumin protocols identified many more patients considered to be malnourished (7,8 ). The authors have tended to interpret this finding as showing the increased sensitivity of prealbumin in detecting malnutrition, rather than the lack of specificity of this test.…”

mentioning

confidence: 99%

Serum Prealbumin: Is It a Marker of Nutritional Status or of Risk of Malnutrition?

2006

View full text Add to dashboard Cite

Improving nutritional screening of hospitalized patients: the role of prealbumin

Abstract: Use of screening questionnaires may miss or delay identification of malnourished patients. PAB screening/assessment may improve identification of those patients requiring nutrition intervention and thus enhance the care of hospitalized individuals.

Cited by 102 publications

References 0 publications

Comparison of two malnutrition risk screening methods (MNA and NRS 2002) and their association with markers of protein malnutrition in geriatric hospitalized patients

Comparison of two malnutrition risk screening methods (MNA and NRS 2002) and their association with markers of protein malnutrition in geriatric hospitalized patients

A nationally representative survey of hospital malnutrition: the Italian PIMAI (Project: Iatrogenic MAlnutrition in Italy) study

Serum Prealbumin: Is It a Marker of Nutritional Status or of Risk of Malnutrition?

Contact Info

Product

Resources

About