Improving nighttime mobility in persons with night blindness caused by retinitis pigmentosa: A comparison of two low-vision mobility devices

Mancil, Rickilyn M.; Mancil, Gary L.; King, Ellis L.; Legault, Claudine; Munday, Julie; Alfieri, Salvatore; Nowakowski, Rod; Blasch, Bruce B.

doi:10.1682/jrrd.2004.08.0091

Cited by 15 publications

(14 citation statements)

References 13 publications

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“…However, the glaucoma rate is higher than the 2.3% in People’s Republic of China21 and 7.5% in Cameroon 10. The usefulness of appropriate low vision devices for visually impaired RP patients cannot be overemphasized 9,22. RP was responsible for 16.6% of low vision patients in a new low vision aid center in southwestern Nigeria 23.…”

Section: Discussionmentioning

confidence: 99%

Clinical presentation and visual status of retinitis pigmentosa patients: a multicenter study in southwestern Nigeria

Onakpoya¹,

Adeoti²,

Oluleye³

et al. 2016

OPTH

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BackgroundTo review the visual status and clinical presentation of patients with retinitis pigmentosa (RP).MethodologyMulticenter, retrospective, and analytical review was conducted of the visual status and clinical characteristics of patients with RP at first presentation from January 2007 to December 2011. Main outcome measure was the World Health Organization’s visual status classification in relation to sex and age at presentation. Data analysis by SPSS (version 15) and statistical significance was assumed at P<0.05.ResultsOne hundred and ninety-two eyes of 96 patients with mean age of 39.08±18.5 years and mode of 25 years constituted the study population; 55 (57.3%) were males and 41 (42.7%) females. Loss of vision 67 (69.8%) and night blindness 56 (58.3%) were the leading symptoms. Twenty-one (21.9%) patients had a positive family history, with RP present in their siblings 15 (71.4%), grandparents 11 (52.3%), and parents 4 (19.4%). Forty (41.7%) were blind at presentation and 23 (24%) were visually impaired. Blindness in six (15%) patients was secondary to glaucoma. Retinal vascular narrowing and retinal pigmentary changes of varying severity were present in all patients. Thirty-five (36.5%) had maculopathy, 36 (37.5%) refractive error, 19 (20%) lenticular opacities, and eleven (11.5%) had glaucoma. RP was typical in 85 patients (88.5%). Older patients had higher rates of blindness at presentation (P=0.005); blindness and visual impairment rate at presentation were higher in males than females (P=0.029).ConclusionClinical presentation with advanced diseases, higher blindness rate in older patients, sex-related difference in blindness/visual impairment rates, as well as high glaucoma blindness in RP patients requires urgent attention in southwestern Nigeria.

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Section: Discussionmentioning

confidence: 99%

Clinical presentation and visual status of retinitis pigmentosa patients: a multicenter study in southwestern Nigeria

Onakpoya¹,

Adeoti²,

Oluleye³

et al. 2016

OPTH

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“…APAC was diagnosed with the following criteria [6][7][8], including substantially elevated IOPand closed angle, acute eye pain, blurred vision,or nausea and vomiting. More importantly, ischemic injury caused by acute ocular hypertension, ciliary or mixed congestion, corneal edema, and glaucoma flecks should be detected.…”

Section: Methodsmentioning

confidence: 99%

Biometric indicators of eyes with occult lens subluxation inducing secondary acute angle closure

et al. 2020

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Background: To compare the anterior biometrics in eyes with secondary acute angle closure induced by occult lens subluxation (ASAC-LS), misdiagnosed as acute primary angle closure (APAC) at the first visit with APAC, chronic primary angle closure glaucoma (CPACG), and cataract. Methods: This retrospective case study included 17 eyes with angel closure due to occult LS, who were misdiagnosed as APAC on their first visit, 56 APAC eyes, 54 CPACG eyes, and 56 cataract eyes. Axial length (AL), central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth (AD) and lens thickness (LT) were recorded. Lens position (LP), relative lens position (RLP), corrected lens position (CLP) were calculated. Quantitative data were subject to one-way analysis of variance and correlation analysis. Categorical data were analyzed using the chi-squared test. Receiver operating characteristic (ROC) curves were plotted to obtain a suitable cutoff value of ocular biometrics. Results: The ASAC-LS patients had a longer ocular axial length than APAC and CPACG patients. Central corneal thickness of the ASAC-LS patients was not significantly different from APAC patients, but was significantly different from CPACG and cataract patients. The APAC patients had the smallest ACD, while the ASAC-LS patients had the smallest AD. The ASAC-LS patients had the largest lens thickness. According to ROC curve analysis, RLP, ACD, AD, CLP, LP had high power of discrimination. Conclusions: This study revealed that LS secondary PAC patients had a shallower AD, thicker CCT comparing to those of APAC, CPACG and cataract patients. For patients with acute angle-closure glaucoma, it is necessary to exclude lens zonula relaxation. Trial registration: NCT03752710, retrospectively registered.

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“…APACG was diagnosed based on the presence of the following characteristics [ 15 – 17 ]: (1) acute increases in IOP and angle closure; (2) acute ophthalmalgia, blurred vision, or nausea and vomiting; and (3) ischemic damage caused by acute ocular hypertension, as well as by ciliary or mixed injection, corneal edema, and glaucomatous flecks.…”

Section: Methodsmentioning

confidence: 99%

Ocular Biometry in Primary Angle-Closure Glaucoma Associated with Retinitis Pigmentosa

Ouyang

Yang

et al. 2017

Journal of Ophthalmology

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Background Retinitis pigmentosa (RP) comprises a group of inherited disorders in which patients typically lose night vision in adolescence and then lose peripheral vision in young adulthood before eventually losing central vision later in life. A retrospective case-control study was performed to evaluate differences in ocular biometric parameters in primary angle-closure glaucoma (PACG) patients with and without concomitant RP to determine whether a relationship exists between PACG and RP. Methods We used ultrasound biomicroscopy (UBM) to measure anterior chamber depth (ACD). A-scan biometry was carried out to measure lens thickness (LT) and axial length (AL). Propensity score matching and mixed linear regression model analysis were conducted. 23 patients with chronic primary angle-closure glaucoma (CPACG) associated with RP, 21 patients with acute primary angle-closure glaucoma (APACG) associated with RP, 270 patients with CPACG, and 269 patients with APACG were recruited for this study. Results There were no significant differences on ACDs, ALs, and relative lens position (RLP) (P > 0.05) between patients with PACG associated with RP and patients with PACG; however, patients with APACG associated with RP had a significantly greater LT than patients with APACG (P < 0.05). Conclusion Patients with PACG associated with RP had the same biometric parameter characteristic as the patients with CPACG and APACG. This may suggest that RP is a coincidental relationship with angle-closure glaucoma.

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Improving nighttime mobility in persons with night blindness caused by retinitis pigmentosa: A comparison of two low-vision mobility devices

Cited by 15 publications

References 13 publications

Clinical presentation and visual status of retinitis pigmentosa patients: a multicenter study in southwestern Nigeria

Clinical presentation and visual status of retinitis pigmentosa patients: a multicenter study in southwestern Nigeria

Biometric indicators of eyes with occult lens subluxation inducing secondary acute angle closure

Ocular Biometry in Primary Angle-Closure Glaucoma Associated with Retinitis Pigmentosa

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