Improving methodological aspects of the analysis of five regulated haloacetic acids in water samples by solid-phase extraction, ion-pair liquid chromatography and electrospray tandem mass spectrometry

Prieto-Blanco, M.C.; Alpendurada, M.F.; López-Mahı́a, Purificación; Muniategui-Lorenzo, Soledad; Prada‐Rodríguez, D.; Machado, Sérgio Luiz de Oliveira; Gonçalves, C.

doi:10.1016/j.talanta.2012.02.061

Cited by 34 publications

(20 citation statements)

References 32 publications

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“…Differences in sample processing existed however (including the initial sample volume and elution conditions) and inconsistencies were partially attributed to these. On the contrary, results for Oasis HLB were more consistent with previous research and those of Isolute ENV+ even showed improved performances with the simplified elution conditions used in this work [24]. The endpoint was not just to recover the 10 selected HAAs, but mainly to develop a flexible method for other ionic organic contaminants in drinking water.…”

Section: Selection Of Spe Sorbentsupporting

confidence: 88%

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Suspect screening of halogenated carboxylic acids in drinking water using ion exchange chromatography – high resolution (Orbitrap) mass spectrometry (IC-HRMS)

Gallidabino

Hamdan

Murphy

et al. 2018

Talanta

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Retrospective in silico screening of analytical data for the identification of new or emerging disinfection by-products in drinking waters could be useful to assess quality and potential hazards, as well as help implement mitigation procedures more rapidly. Herein, the first study coupling ion exchange chromatography (IC) with high resolution mass spectrometry (HRMS) for the determination of halogenated carboxylic acid disinfectant by-products is reported. Separation was achieved using a Metrohm A Supp 5 column and a NaCO/NaHCO gradient eluent from 1/0.31 to 10/3.1mM. A variety of solid phase extraction (SPE) sorbents were tested for added selectivity to organic ions and Isolute ENV+ cartridges were selected because of their best overall extraction performance. Method LODs were in the μgL concentration range, with R ≥ 0.99 for all the analytes, and isobaric ions could be easily discriminated using HRMS. The method was applied to municipal drinking water. Targeted quantitative analysis revealed the presence of 10 haloacetic acids at levels not exceeding the limits set by WHO and USEPA. Furthermore, suspect screening for additional halogenated carboxylic acids via retrospective HRMS data analysis also indicated the presence of other iodinated HAAs and chlorinated propionic acids, of which one (i.e. monochloropropionic acid) is discussed here for the first time. Most importantly, several potential suspects could be eliminated from further consideration through HRMS data analysis alone. To our knowledge, this represents the first time that a retrospective IC-HRMS screen of halogenated carboxylic acids in drinking water has been reported.

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Section: Selection Of Spe Sorbentsupporting

confidence: 88%

“…Results for LiChrolut EN were somewhat unexpected and were inconsistent with some previous works which showed better recoveries for these HAAs [18,24]. Differences in sample processing existed however (including the initial sample volume and elution conditions) and inconsistencies were partially attributed to these.…”

Section: Selection Of Spe Sorbentcontrasting

confidence: 75%

Suspect screening of halogenated carboxylic acids in drinking water using ion exchange chromatography – high resolution (Orbitrap) mass spectrometry (IC-HRMS)

Gallidabino

Hamdan

Murphy

et al. 2018

Talanta

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“…Researchers have embraced MS for HAAs analysis (Duan et al, 2011;Zhang et al, 2011;Li et al, 2012Li et al, , 2013Prieto-Blanco et al, 2012;Casas Ferreira et al, 2013;Hung and Her, 2013;Luo et al, 2013). Derivatization methods (Li et al, 2013) convert the HAAs to volatile species amenable for GC-MS analysis, similar to USEPA methods (USEPA, 1995(USEPA, , 2003 and others (Hammami and Driss, 2013;Liu et al, 2013), but have high labor costs.…”

Section: Introductionmentioning

confidence: 99%

“…An effort to automate the grab sample derivatization (Casas Ferreira et al, 2013) proved successful, thus minimizing the labor. Tandem MS techniques typically use some form of pretreatment or preconcentration coupled with GC (Li et al, 2013), high pressure liquid chromatography (HPLC) (Li et al, 2012;Prieto-Blanco et al, 2012), ultra pressure LC (UPLC) (Duan et al, 2011;Luo et al, 2013), or capillary electrophoresis (CE) (Zhang et al, 2011;Hung and Her, 2013) to detect and quantify HAAs. Two reports (Duan et al, 2011;Li et al, 2012) and USEPA 557 (USEPA, 2009) use direct aqueous injection and avoid complex pretreatment and preconcentration techniques with excellent results.…”

Section: Introductionmentioning

confidence: 99%

“…Traditionally, HAAs preconcentration has used techniques such as liquid-liquid extraction (USEPA, 1995(USEPA, , 2003Hammami and Driss, 2013;Liu et al, 2013) or solid phase extraction Paull and Barron, 2004;Ding and Rogers, 2010;Prieto-Blanco et al, 2012;Kubáň et al, 2012;Nsubuga and Basheer, 2013) via manual or semi-automated analysis. For continuous, on-line, real-time analysis, an automated preconcentration module must do all of the sample handling and preparation steps for SPE preconcentration from sample intake and acidification to elution onto the analyzer for injection.…”

Section: Introductionmentioning

confidence: 99%

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A fully-automated analyzer for determining haloacetic acid concentrations in drinking water

2014

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A convenient and sensitive method for haloacetic acid analysis in tap water by on-line field-amplified sample-stacking CE-ESI-MS

Hung

Her

2013

J. Sep. Science

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In this study, we propose a simple strategy based on flow injection and field-amplified sample-stacking CE-ESI-MS/MS to analyze haloacetic acids (HAAs) in tap water. Tap water was passed through a desalination cartridge before field-amplified sample-stacking CE-ESI-MS/MS analysis to reduce sample salinity. With this treatment, the signals of the HAAs increased 300- to 1400-fold. The LODs for tap water analysis were in the range of 10 to 100 ng/L, except for the LOD of monochloroacetic acid (1 μg/L in selected-ion monitoring mode detection). The proposed method is fast, convenient, and sensitive enough to perform on-line analysis of five HAAs in the tap water of Taipei City. Four HAAs, including trichloroacetic acid, dichloroacetic acid, dibromoacetic acid, and monobromoacetic acid, were detected at concentrations of approximately 1.74, 1.15, 0.16, and 0.15 ppb, respectively.

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Improving methodological aspects of the analysis of five regulated haloacetic acids in water samples by solid-phase extraction, ion-pair liquid chromatography and electrospray tandem mass spectrometry

Cited by 34 publications

References 32 publications

Suspect screening of halogenated carboxylic acids in drinking water using ion exchange chromatography – high resolution (Orbitrap) mass spectrometry (IC-HRMS)

Suspect screening of halogenated carboxylic acids in drinking water using ion exchange chromatography – high resolution (Orbitrap) mass spectrometry (IC-HRMS)

A fully-automated analyzer for determining haloacetic acid concentrations in drinking water

A convenient and sensitive method for haloacetic acid analysis in tap water by on-line field-amplified sample-stacking CE-ESI-MS

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