Abstract:(2015). Improving human understanding and design of complex multi-level systems with animation and parametric relationship supports. Design Science, 1, e3 doi:10.1017/dsj. 2015
AbstractComplex systems are challenging to design, particularly when they contain multi-level organizations with non-obvious relationships among design components. Here, we investigate engineering students' capacity to search for optimal nanoscale biosystem designs with stochastic component and system behaviors. The study aims to chara… Show more
“…In the simulation, each myosin's structure was designable and linked to behaviors that influence design performance [15]. Human designers interacting with the agent-based simulation gained understanding of the system that improved their ability to search a parametric design space [18]. These studies offer validation for using a parametric design representation for the human-in-the-loop approach.…”
Section: Cognitive Processes For Complex Systems Designmentioning
confidence: 99%
“…Once computational biological models are validated, they may be utilized to evaluate new system configurations that are representative of designs. In our past work, agent-based myosin models were validated with empirical data [16] and provided a means for evaluation in engineering optimization tasks representative of myosin technologies [18]. Since these tasks represent a variety of technologies, an interesting design problem emerges when considering the best set of myosins for use in all technologies, such as selecting myosins from a design catalog.…”
Section: Cognitive Processes For Complex Systems Designmentioning
confidence: 99%
“…In mechanical design domains, there is a great opportunity for leveraging biological components and design principles to develop technologies including nano-actuators, smart contractile materials, and shear-triggered medicines [14]. Recently, we have demonstrated the feasibility in utilizing computational approaches for designing myosin motor protein biosystems informed by scientific experiments [15,16] and have conducted empirical studies to understand and improve human bio-based design decision making [17,18]. In this work, findings and processes from these past studies are utilized to propose and implement a new general methodology that bridges science and design for bio-based product development.…”
New opportunities in design surface with scientific advances: however, the rapid pace of scientific discoveries combined with the complexity of technical barriers often impedes new product development. Bio-based technologies, for instance, typically require decisions across complex multiscale system organizations that are difficult for humans to understand and formalize computationally. This paper addresses such challenges in science and design by weaving phases of empirical discovery, analytical description, and technological development in an integrative “D3 Methodology.” The phases are bridged with human-guided computational processes suitable for human-in-the-loop design approaches. Optimization of biolibraries, which are sets of standardized biological parts for adaptation into new products, is used as a characteristic design problem for demonstrating the methodology. Results from this test case suggest that biolibraries with synthetic biological components can promote the development of high-performance bio-based products. These new products motivate further scientific studies to characterize designed synthetic biological components, thus illustrating reciprocity among science and design. Successes in implementing each phase suggest the D3 Methodology is a feasible route for bio-based research and development and for driving the scientific inquiries of today toward the novel technologies of tomorrow.
“…In the simulation, each myosin's structure was designable and linked to behaviors that influence design performance [15]. Human designers interacting with the agent-based simulation gained understanding of the system that improved their ability to search a parametric design space [18]. These studies offer validation for using a parametric design representation for the human-in-the-loop approach.…”
Section: Cognitive Processes For Complex Systems Designmentioning
confidence: 99%
“…Once computational biological models are validated, they may be utilized to evaluate new system configurations that are representative of designs. In our past work, agent-based myosin models were validated with empirical data [16] and provided a means for evaluation in engineering optimization tasks representative of myosin technologies [18]. Since these tasks represent a variety of technologies, an interesting design problem emerges when considering the best set of myosins for use in all technologies, such as selecting myosins from a design catalog.…”
Section: Cognitive Processes For Complex Systems Designmentioning
confidence: 99%
“…In mechanical design domains, there is a great opportunity for leveraging biological components and design principles to develop technologies including nano-actuators, smart contractile materials, and shear-triggered medicines [14]. Recently, we have demonstrated the feasibility in utilizing computational approaches for designing myosin motor protein biosystems informed by scientific experiments [15,16] and have conducted empirical studies to understand and improve human bio-based design decision making [17,18]. In this work, findings and processes from these past studies are utilized to propose and implement a new general methodology that bridges science and design for bio-based product development.…”
New opportunities in design surface with scientific advances: however, the rapid pace of scientific discoveries combined with the complexity of technical barriers often impedes new product development. Bio-based technologies, for instance, typically require decisions across complex multiscale system organizations that are difficult for humans to understand and formalize computationally. This paper addresses such challenges in science and design by weaving phases of empirical discovery, analytical description, and technological development in an integrative “D3 Methodology.” The phases are bridged with human-guided computational processes suitable for human-in-the-loop design approaches. Optimization of biolibraries, which are sets of standardized biological parts for adaptation into new products, is used as a characteristic design problem for demonstrating the methodology. Results from this test case suggest that biolibraries with synthetic biological components can promote the development of high-performance bio-based products. These new products motivate further scientific studies to characterize designed synthetic biological components, thus illustrating reciprocity among science and design. Successes in implementing each phase suggest the D3 Methodology is a feasible route for bio-based research and development and for driving the scientific inquiries of today toward the novel technologies of tomorrow.
“…A human designer may then steer computational processes with a "human-in-the-loop" design approach by making highlevel decisions that guide the computational processes towards more beneficial solutions . In this framework, a human designer could potentially steer computational processes based on knowledge of multilevel parameter interactions that influence qualitatively distinct emergent system behaviours (Egan et al 2015c) and could potentially be difficult to formalize computationally. Empirical research studies can play a role in scientifically determining the most effective way to interface human and computational decision-making processes for solving such design problems.…”
Section: Human and Computational Design Approachesmentioning
confidence: 99%
“…One of our recent human participant experiments demonstrated that human understanding of qualitative behaviours across complex system scales improves human design decision-making performance (Egan et al 2015c). However, a precise cognitive mechanism for how designers translate such understanding towards better design decision-making was not identified.…”
Section: Potential Cognitive Phenomenon To Investigatementioning
Human and computational approaches are both commonly used to solve design problems, and each offers unique advantages. Human designers may draw upon their expertise, intuition, and creativity, while computational approaches are used to algorithmically configure and evaluate design alternatives quickly. It is possible to leverage the advantages of each with a human-in-the-loop design approach, which relies on human designers guiding computational processes; empirical design research for better understanding human designers' strengths and limitations can inform the development human-in-the-loop design approaches. In this chapter, the advantages of human and computational design processes are outlined, in addition to how they are researched. An empirical research example is provided for conducting human participant experiments and simulating human design problem-solving strategies with software agent simulations that are used to develop improved strategies. The chapter concludes by discussing general considerations in human and computational research, and their role in developing new human-in-the-loop design processes for complex engineering applications.
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