This article develops a pragmatic approach to optimize child healthy growth and upcoming public health by optimizing gestational foetal cell omics. A particular emphasis is placed on obesity. This is also to minimize risks from metabolic complexities. Affecting genome properties in foetal cells may be realized by optimizing pregnant women's life style and food regimens. Optimizing exercise intensity, frequency and timing, circadian eating occasions, social interactions and atmosphere and exposure to fluctuating environments are to be pursued.