Improving cardiovascular risk stratification in essential hypertensive patients by indexing left ventricular mass to height2.7

Abstract

Our data indicate that a consistent portion of essential hypertensive patients are positive for LVH by the criterion of LVM indexed to height(2.7), but not to BSA; this population is characterized by an unhealthy metabolic profile as well as by the presence of extracardiac organ damage. They also suggest that, in order to improve cardiovascular stratification, LVM should be routinely indexed to both BSA and height(2.7) and patients categorized according to the consistency of both criteria.

Non-hemodynamic factors associated to the risk of developing hypertensive cardiopathy

“…It has been observed that in patients treated with astatines cardiovascular risk has not been reduced when HDL remains low [64]. Elevated levels of uric acid was a risk factor for hypertensive cardiopathy, and some studies [33,55], coincide with our indings.…”

“…As in the present series, Cuspidi [55] and Yeboah [63], did not ind any nonindependent association between high levels of triglycerides and the risk of LVH.…”

Design and validation of an Index to predict the development of Hypertensive Cardiopathy

“…For the latter there is currently an index designed in our context, consisting on a multivariate study, based on a case-control study [24]. Although the study showed an adequate internal and external validity [24], it is necessary to improve it based on the fact that the risk of developing depends not only on multiple causes but also with permanent evolutional changes, as has been demonstrated by several studies [21,[24][25][26][27][28][29]. Another aspect to highlight is that the Hosmer and Lemeshow Test X 2 = 5.059 degrees of freedom 8 p = 0.0751. new proposal is based on a cohort study, which have demonstrated a better capacity to predict risks.…”

The Association of Long-Functioning Hemodialysis Vascular Access with Prevalence of Left Ventricular Hypertrophy in Kidney Transplant Recipients

“…LVM was indexed separately for BSA (LVMI/BSA) and height (LVMI/height 2.7 ). Thus, patients were diagnosed with LVH based on two separate criteria: LVMI/BSA > 110 g/m 2 for women and >134 g/m 2 for men [20] or LVMI/height 2.7 > 45 g/m 2.7 for women and >49 g/m 2.7 for men [21]. …”