Improving adherence to acne treatment: the emerging role of application software

Park, Chanhyun; Kim, Gilwan; Patel, Isha; Tan, Xi

doi:10.2147/ccid.s46051

Cited by 13 publications

(8 citation statements)

References 22 publications

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“…Most studies on the topical treatment of acne have focused on adherence to therapy, the reasons for adherence, and suggested solutions. 3–11 This study revealed that discontinuation occurred mostly with the use of retinoids (40%), benzoyl peroxide combinations (44.1%), and retinoid combinations (60%). Furthermore, the reasons for discontinuation of these treatments were reported as a result of side effects, with rates of 50%, 33.3%, and 65.7%, respectively.…”

Section: Discussionmentioning

confidence: 88%

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Topical treatment of acne vulgaris: efficiency, side effects, and adherence rate

Dikicier

2019

J Int Med Res

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Objective Adherence is a problem in the topical treatment of acne. This study was designed to evaluate the efficiency of current topical treatment and adherence in patients. Methods Patients with acne vulgaris who had recently been prescribed a topical therapy were selected. A dermatologist-directed questionnaire was completed. Demographic data, acne severity, treatment and the manner of use, side effects, and reason for discontinuation were recorded. Results A total 250 patients were included, 178 female (71.2%) and 72 male (28.8%) participants, mean age was 18.6 ± 2.8 years. Of 250 patients, 114 (45.6%) had given up therapy for two reasons: unresponsiveness in 71 (62.3%) and side effects in 43 (37.7%) patients. For antibacterial treatments, the rate of unresponsiveness was higher but the rate of side effects was lower. Discontinuation owing to unresponsiveness was higher in patients with severe acne. Side effects were higher in patients with comedonal-type acne. The lowest rates of side effects and discontinuation were among every-other-night users. Conclusion In this study, patients with acne gave up treatment owing to side effects and unresponsiveness, which reduced the treatment efficiency.

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Section: Discussionmentioning

confidence: 88%

“…These findings indicate that side effects and unresponsiveness are the main reasons for discontinuation of topical treatment in patients with acne. A literature review by Park et al 5 revealed that adherence was higher among patients with acne taking oral medication than in those using topical medication.…”

Section: Discussionmentioning

confidence: 99%

Topical treatment of acne vulgaris: efficiency, side effects, and adherence rate

Dikicier

2019

J Int Med Res

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“…Snyder et al stated that a physician’s ability to convey information about the medication is critical for treatment success and patient satisfaction [ 9 ]. For effective patient education and counselling on the treatment of chronic disease, various means of information such as reading materials, videos, and reminders may be utilized [ 21 – 23 ]. Recent studies have shown that written counselling significantly improved adherence in acne patients [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Use of Supplementary Patient Education Material Increases Treatment Adherence and Satisfaction Among Acne Patients Receiving Adapalene 0.1%/Benzoyl Peroxide 2.5% Gel in Primary Care Clinics: A Multicenter, Randomized, Controlled Clinical Study

Myhill¹,

Coulson

Nixon³

et al. 2017

Dermatol Ther (Heidelb)

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IntroductionPoor adherence to acne treatment may lead to unnecessary treatments, increased healthcare costs, and reduced quality of life (QoL). This multicenter study evaluated the effect of supplementary patient education material (SEM) (a short video, information card, and additional information available online) on treatment adherence and satisfaction among acne patients treated with the fixed-dose combination adapalene 0.1%/benzoyl peroxide 2.5% gel (A/BPO) in primary care clinics versus (1) standard-of-care patient education (SOCPE) (package insert and oral instruction) and (2) SOCPE plus more frequent clinic visits.MethodsSubjects with acne were randomized to receive once-daily A/BPO for 12 weeks plus (1) SEM in addition to SOCPE; (2) SOCPE only with two additional visits; or (3) SOCPE only. Other assessments included a subject appreciation questionnaire, a physician questionnaire, and safety.ResultsNinety-seven subjects were enrolled. At baseline, most (87.6%) had mild to moderate acne. Better adherence was observed in the A/BPO + SEM group compared with A/BPO + more visits or A/BPO alone [mean 63.1%, 48.2% (p = 0.0206), and 56.5%, respectively]. The A/BPO + SEM group had more subjects with greater than 75% adherence (45%, 30.4%, and 25%, respectively). According to the subject appreciation questionnaire, the SEM was more helpful to adhere to treatment (56.7%) versus more visits (32.3%) and A/BPO alone (15.2%), better use the product (70%, 61.3%, and 54.5%, respectively), and better manage skin irritation (53.3%, 48.4%, and 36.4%, respectively). All physicians were satisfied with the SEM and 90% would consider using it in their practice. Safety assessment showed fewer treatment-related adverse events in the A/BPO + SEM group.ConclusionUse of the SEM may increase adherence of acne patients treated with once-daily A/BPO gel in primary care, consequently improving treatment and QoL in the long term.FundingNestle Skin Health-Galderma R&D.Trial RegistrationClinicalTrials.gov Identifier: NCT02307266.

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“…Young people are nowadays on average more engaged with technology and the internet than previous generations ( 5 ). This familiarity can positively influence the satisfaction of adolescent patients with teledermatology, since for most of these patients the correct handling of smartphones and telemedicine programs does not involve a big learning effort ( 5 , 8 ). Furthermore, such teledermatological check-ups might save patients’ time and avoid absences either at school or at work ( 5 , 9 ).…”

Section: Discussionmentioning

confidence: 99%

Randomized Open-Label Trial Comparing Teledermatology vs. Face-to-Face Consultation in the Follow-Up of Patients with Mild-to-Moderate Acne

Heidemeyer¹,

Bodle²,

ll³

et al. 2023

Acta Inform Med

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Background: Acne vulgaris is one of the most common dermatological diseases, especially in adolescents and young adults. Objective: The current study aimed to compare teledermatology versus face-to-face consultation in the follow-up of patients with mild-to-moderate acne. Methods: In this investigator-initiated, parallel arms, open-label, randomized clinical trial, after screening, participants were randomly assigned in a 1:1 ratio to be followed up through teledermatology or standard face-to-face consultations for a period of 6 months. The primary endpoint was the cumulative time spent by physician for consultations or online assessments. Results: 24 patients (21 females and 3 males; mean age 23.0 ± 3.3 years) underwent randomization in the two study groups. In intention-to-treat analysis, the cumulative time spent by physician was higher in the teledermatology group compared to face-to-face consultations with an average difference of 8:24 mm:ss (95% CI: 1:17-15:31). However, the cumulative time spent by the patient was significantly lower in the teledermatology group (mean difference 1:21:39 hh:mm:ss; 95% CI: 41:51-2:01:27). An optimal reduction of acne-severity was observed in both groups, without significant differences between them. The patient’s satisfaction did not change significantly over time and between groups, and was generally quite high. AEs were reported by one patient in the teledermatology group and four patients in the consultation group. Conclusion: Acne might be an optimal disease to be followed up using a teledermatology platform, to relieve the burden on patients and medical staff. However, it is necessary to implement more user-friendly platforms in order to achieve the best possible results in the treatment and follow-up of acne patients.

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Improving adherence to acne treatment: the emerging role of application software

Cited by 13 publications

References 22 publications

Topical treatment of acne vulgaris: efficiency, side effects, and adherence rate

Topical treatment of acne vulgaris: efficiency, side effects, and adherence rate

Use of Supplementary Patient Education Material Increases Treatment Adherence and Satisfaction Among Acne Patients Receiving Adapalene 0.1%/Benzoyl Peroxide 2.5% Gel in Primary Care Clinics: A Multicenter, Randomized, Controlled Clinical Study

Randomized Open-Label Trial Comparing Teledermatology vs. Face-to-Face Consultation in the Follow-Up of Patients with Mild-to-Moderate Acne

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