Abstract:The preparation of ethyl acetoacetate is a distinctive,
century-old
classic organic chemistry laboratory project. Ethyl acetate and sodium
metal (sodium ethoxide) are reacted by Claisen ester condensation
to produce the sodium salt of ethyl acetoacetate and then obtain the
refined product by acidification as well as washing, drying, and distillation
under reduced pressure. This article analyzed the reasons for the
low product yield and poor purity of the traditional experimental
method and found that ethanol w… Show more
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