Jelnes R, Biilow J, Tannesen KH. Subcutaneous adipose tissue blood flow in the forefoot during 24 hours. Labelling pattern and reproducibility. Scand J Clin Lab Invest 1987; 47: 223-227.Wash-out of '33xenon from a local depot in the subcutaneous adipose tissue in the forefoot was measured continuously during 24 hours on subsequent recordings in 51 feet (normal circulation: 10, intermittent claudication: 22 and ischaemic nocturnal rest pain: 19) with a mean time interval of 26 days (range: 3-90 days). The patients were studied under two different conditions. Firstly, during the day in the erect position, awake (sitting, standing and quiet walking) and secondly, during night hours in the supine position, asleep. The coefficient of variation of nocturnal adipose tissue blood flow was calculated to lo%, and for the ratio of blood flow from day to night to 5%. The method is thus considered apt as a monitor in the treatment of peripheral vascular disease, for example, surgery and medical therapy. As predominant source of error is the formation of oedema. 10 5 ;CV= G7mean. RSBFrelative subcutaneous blood flow from day to night. Scand J Clin Lab Invest Downloaded from informahealthcare.com by University of Melbourne on 11/26/14 For personal use only. Scand J Clin Lab Invest Downloaded from informahealthcare.com by University of Melbourne on 11/26/14For personal use only.