Improvement of Quality of Life in Patients with Peripheral Neuropathy Treated with a Fixed Dose Combination of High-Dose Vitamin B1, B6 and B12: Results from a 12-week Prospective Non-interventional Study in Indonesia

Hakim, Manfaluthy; Kurniani, Nani; Pinzon, Rizaldy Taslim; Tugasworo, Dodik; Basuki, Mudjiani; Haddani, Hasnawi; Pambudi, Pagan; Fitri, Aida; Wuysang, Audry Devisanty

doi:10.4172/2167-0870.1000343

Cited by 3 publications

(4 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Additionally, it is well-tolerated and has been associated with enhanced quality of life for patients. [45].…”

Section: Discussionmentioning

confidence: 99%

“…If the patients had needed post-dosing vitamin supplements, the results would not have been influenced only by the studied combination; • We did not use specific scales for the assessment of neuropathic pain [69] because the patients had mixed pain, as stated in other studies [70]. We considered that the McGill Pain Questionnaire offered a suggestive image of our patient's pain status, as other studies show [45].…”

Section: Limits Of Our Studymentioning

confidence: 99%

See 1 more Smart Citation

Quality of Life in Patients with Lumbosacral Radicular Syndrome and Complete Rehabilitation Program (PRISUM PHSD/1/2022)

2024

J Family Med Prim Care Open Acc

View full text Add to dashboard Cite

Worldwide, Lumbosacral Radicular Syndrome (L.R.S.) represents one of the most common lumbar spine problems, inducing disability, reduced quality of life, and working capability. We performed a prospective, double-blind, randomized study in the Departments of Physical Medicine and Rehabilitation, Filantropia Hospital, Craiova, and Techirghiol Balneal and Rehabilitation Sanatorium from June to October 2022. We analyzed the effects of ProHumano+ SpineDinamic (PHSD) on the severity reduction of radicular pain and improvement of quality of life in patients with L.R.S. over three months. A total of 247 patients were randomly divided into two groups: Group 1 (151 patients) received 10 sessions of the rehabilitation program and PHSD (daily, three months), and Group 2 (96 patients) received ten sessions of the rehabilitation program and placebo (daily, three months). Conventional physical therapy (transcutaneous nerve stimulation, ultra-sound, and low-intensity laser treatment) and kinetic program represented the components of a rehabilitation program. Statistical analysis was performed using Microsoft Excel (Microsoft Corp., Redmond, WA, U.S.A.), together with the XLSTAT add-on (Addinsoft SARL, Paris, France). All patients had a favorable evolution, but the difference was significantly statistic for G1 patients. These results concluded that daily PHSD for three months naturally affected clinical and functional status in L.R.S.

show abstract

“…Additionally, it is well-tolerated and has been associated with enhanced quality of life for patients. [45].…”

Section: Discussionmentioning

confidence: 99%

Section: Limits Of Our Studymentioning

confidence: 99%

Quality of Life in Patients with Lumbosacral Radicular Syndrome and Complete Rehabilitation Program (PRISUM PHSD/1/2022)

2024

J Family Med Prim Care Open Acc

View full text Add to dashboard Cite

show abstract

“…Higher scores indicated better perceived health in the particular domain. The Short Form-8 Health Survey was found to be reliable and valid in both Chinese and Indonesian samples [ 30 , 31 ].…”

Section: Methodsmentioning

confidence: 99%

Testing of a Dual Process Model to Resolve the Socioeconomic Health Disparities: A Tale of Two Asian Countries

Cheng

Atal

et al. 2021

IJERPH

View full text Add to dashboard Cite

A wealth of past studies documented that individuals of lower socioeconomic status (SES) are more susceptible to both acute and chronic life stress than those of higher SES, but some recent evidence documents that not all individuals from the lower SES group experience immense stress. The present study was grounded in theories of coping and psychological adjustment, and a dual process model was formulated to address some resolved issues regarding socioeconomic disparities in health. For a robust test of the proposed dual process model, data were collected from two Asian countries—Hong Kong and Indonesia—with different socioeconomic heritage and conditions. Consistent with the predictions of our model, the present findings revealed that coping flexibility was a psychological mechanism underlying the positive association between social capital and health for the lower SES group, whereas active coping was a psychological mechanism underlying this positive association for the higher SES group. These patterns of results were largely replicable in both Asian samples, providing robust empirical support for the proposed dual process model.

show abstract

“…(Altun Kurutaş, 2016) Pemberian kombinasi vitamin B yang terdiri dari vitamin B1, B6, dan B12 dapat membantu mengurangi gejala neuropati perifer secara efektif. (Hakim et al, 2018) Pada sistem saraf pusat, vitamin B terutama vitamin B6 dan B12 bermanfaat dalam metabolisme asam folat dan homosistein. Fungsi lain vitamin B pada sistem saraf perifer bermanfaat dalam membantu mengoptimalkan fungsi saraf.…”

Section: Pembahasanunclassified

Manfaat Terapi Tambahan Vitamin pada Pasien Nyeri Neuropati Diabetika

Asisaratu,

Pinzon,

Pramudita

2023

jfu

View full text Add to dashboard Cite

Latar Belakang: Nyeri neuropati diabetika menjadi komplikasi penyakit Diabetes Mellitus yang paling sering terjadi dan dapat menjadi beban sehingga dibutuhkan pengobatan optimal. Pengobatan saat ini yaitu terapi simtomatik dengan kontrol indeks glikemik namun belum dapat mencapai target optimal. Penelitian terdahulu menunjukkan suplementasi vitamin B dan vitamin D dapat memberikan pengurangan nyeri yang signifikan. Cara Kerja: Penelitian ini dilakukan menggunakan metode kohort retrospektif. Pengambilan sampel dilakukan menggunakan metode consecutive sampling dengan total sampel 107 subjek yang mendapatkan terapi simtomatik atau terapi simtomatik ditambah vitamin. Terapi diberikan selama tiga bulan. Pengukuran skala nyeri dilakukan dengan menggunakan Neuropathic Pain Scale. Hasil: Penelitian ini membandingkan subjek dalam tiga kelompok perbandingan. Pada kelompok perbandingan pertama, pengurangan nyeri paling besar pada kelompok terapi simtomatik ditambah vitamin (39,50±14,222) (p=0,000). Pada kelompok perbandingan kedua, pengurangan nyeri paling besar terdapat pada kelompok terapi simtomatik ditambah kombinasi vitamin B dan vitamin D 1000 IU (53,00±6,749) (p=0,000). Pada kelompok perbandingan ketiga, pengurangan nyeri paling besar terdapat pada kelompok terapi simtomatik ditambah vitamin D 1000 IU (44,00±8,944) (p=0,088). Kesimpulan: Terapi tambahan vitamin mengakibatkan pengurangan nyeri yang lebih besar secara bermakna dibandingkan terapi simtomatik saja. Tidak terdapat perbedaan penurunan nyeri yang bermakna antara penambahan vitamin D 400 IU dengan vitamin D 1000 IU. Kata kunci: intensitas nyeri; nyeri neuropati diabetika; vitamin B; vitamin D

show abstract

Improvement of Quality of Life in Patients with Peripheral Neuropathy Treated with a Fixed Dose Combination of High-Dose Vitamin B1, B6 and B12: Results from a 12-week Prospective Non-interventional Study in Indonesia

Cited by 3 publications

References 0 publications

Quality of Life in Patients with Lumbosacral Radicular Syndrome and Complete Rehabilitation Program (PRISUM PHSD/1/2022)

Quality of Life in Patients with Lumbosacral Radicular Syndrome and Complete Rehabilitation Program (PRISUM PHSD/1/2022)

Testing of a Dual Process Model to Resolve the Socioeconomic Health Disparities: A Tale of Two Asian Countries

Manfaat Terapi Tambahan Vitamin pada Pasien Nyeri Neuropati Diabetika

Contact Info

Product

Resources

About