Improvement of hepatic dearterialization: A case report

Idema, Albertus A. J.; Tjiong, Harry S. L.; Oldhoff, J

doi:10.1002/jso.2930130303

Cited by 8 publications

(3 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The dearterialization caused a transient increase in serum liver enzyme levels, but no signs of hepatic insufficiency were observed in our series; this is in accord with many earlier reports [10,30]. Tolerance to hepatic dearterialization requires, however, an intact portal vein [10,28].…”

Section: Discussionsupporting

confidence: 92%

“…Liver metastases from carcinoid tumors have been treated with resection [22,23], enucleation [24,25], hepatic artery ligation [26], and total hepatic dearterialization [27,28]. Hepatic artery ligation and total hepatic dearterialization give a good symptomatic result in about 50% of patients treated [16][17][18], but the operations are followed by a significant mortality rate [16][17][18].…”

Section: Discussionmentioning

confidence: 99%

“…Preliminary data suggest that angiography in combination with computed tomography might improve the accuracy [31]. Neither is urinary excretion of 5-HIAA a good criterion of tumor size [28]. Normal levels do not exclude the possibility of carcinoid tumor growth and, on the other hand, patients with limited tumor mass can have high 5-HIAA levels.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Temporary liver dearterialization in patients with metastatic carcinoid disease

et al. 1982

View full text Add to dashboard Cite

The surgical treatment of liver metastases from carcinoid tumors is burdened by a relatively poor symptomatic relief and a high mortality rate. Temporary liver dearterialization, separating the operative trauma from the temporary hepatic occlusion, may have advantages. We have utilized this treatment in 16 patients. The effect of treatment was registered in symptomatic relief, changes in urinary 5-HIAA, serotonin in platelet-poor plasma, and morphologic changes shown by angiography.Fourteen patients, who underwent only the dearterialization procedure, survived the immediate postoperative period, while 2 patients who had concomitant small bowel resection both died of complications, 1 and 3 months postoperatively, respectively. One patient died, 14 months postoperatively, of the carcinoid disease. All but 1 patient were free from symptoms for at least 6 months. Two patients have had no recurrence of the carcinoid syndrome for 34 and 42 months, respectively. A decrease in urinary 5-HIAA was seen after 6 months in 10 patients, serotonin declined in 7 patients, and angiography showed regression in 7 patients. The results of this study indicate that temporary liver dearterialization is a safe procedure with low mortality and good symptomatic relief from the carcinoid syndrome.Both primary and secondary liver tumors are chiefly supplied by blood from the hepatic artery, which was first shown by Segall in 1923 [1] and later confirmed by others [2,3]. Smaller tumors [4] and Supported by grants from the Swedish Medical Research Council (grant no. 04X-00712).

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Temporary liver dearterialization in patients with metastatic carcinoid disease

et al. 1982

View full text Add to dashboard Cite

show abstract

Surgical Treatment of Functioning Metastatic Carcinoid Tumors

Martin¹

1983

Arch Surg

View full text Add to dashboard Cite

Embolization of the liver in the management of metastatic carcinoid tumors

Mårtensson

Nobin

Bengmark

et al. 1984

Journal of Surgical Oncology

View full text Add to dashboard Cite

Eight patients with metastatic carcinoid tumors and the carcinoid syndrome were treated with gelatin foam embolization of the hepatic arterial tree. The aims were to reduce the tumor mass in the liver and to eliminate the carcinoid syndrome. The effects of the treatment were judged from arteriograms, CT scans, and the levels of serotonin in blood and 5-HIAA in urine, as well as from the clinical symptoms. The mean follow-up time was 12.5 months. In all patients the liver tumor mass was reduced after embolization, and this reduction persisted for at least 6 months in seven patients. After treatment, reduced serotonin levels in blood were measured in four patients and reduced 5-HIAA levels in urine in seven patients. In five patients the carcinoid syndrome disappeared after embolization, but after 6 months two of these five patients had regained symptoms. Adverse reactions were minor consisting of a slight fever, reversibly increased serum levels of liver enzymes, and abdominal pain. In our experience, the hepatic embolization is a simple and safe method of giving relief from the carcinoid syndrome.

show abstract

Improvement of hepatic dearterialization: A case report

Cited by 8 publications

References 9 publications

Temporary liver dearterialization in patients with metastatic carcinoid disease

Temporary liver dearterialization in patients with metastatic carcinoid disease

Surgical Treatment of Functioning Metastatic Carcinoid Tumors

Embolization of the liver in the management of metastatic carcinoid tumors

Contact Info

Product

Resources

About