Improvement of drug delivery micro-circulatory system with a novel pattern of CuO-Cu/blood hybrid nanofluid flow towards a porous stretching sheet

Abstract

Purpose This paper aims to simulate the steady laminar mixed convection incompressible viscous and electrically conducting hybrid nanofluid (CuO-Cu/blood) flow near the plane stagnation-point over a horizontal porous stretching sheet along with an external magnetic field and induced magnetic field effects that can be applicable in the biomedical fields like the flow dynamics of the micro-circulatory system and especially in drug delivery. Design/methodology/approach The basic partial differential equations (PDEs) are altered to a set of dimensionless ordinary differential equations (ODEs) with the help of suitable similarity variables which are then solved numerically using bvp4c scheme from MATLAB. Inasmuch as validation results have shown a good agreement with previous reports, the present novel mass-based algorithm can be used in this problem with great confidence. Governing parameters are both nanoparticle masses, base fluid mass, empirical shape factor of both nanoparticles, suction/injection parameter, magnetic parameter, reciprocal magnetic Prandtl number, Prandtl number, heat source parameter, mixed convection parameter, permeability parameter and frequency ratio. The effect of these parameters on the flow and heat transfer characteristics of the problem is discussed in detail. Findings It is shown that the use of CuO and Cu hybrid nanoparticles can reduce the hemodynamics effect of the capillary relative to pure blood case. Moreover, as the imposed magnetic field enhances, the velocity of the blood decreases. Besides, when the blade shapes for both nanoparticles are taken into account, the local heat transfer rate is maximum that is also compatible with experimental observations. Originality/value An innovative mass-based model of CuO-Cu/blood hybrid nanofluid has been applied. The novel attitude to one-phase hybrid nanofluid model corresponds to considering nanoparticles mass as well as base fluid mass to computing the solid equivalent volume fraction, the solid equivalent density and also solid equivalent specific heat.

Mixed convection stagnation point flow of the blood based hybrid nanofluid around a rotating sphere

“…Subhani and Nadeem 16 studied the behavior of (hybrid nanofluid) over the stretching surface. Dinarvand et al 17 introduced /blood (hybrid nanofluid) circulation on a permeable stretching sheet, which is an advanced density concept, that can be a favorable model in medical sciences, particularly in cancer therapy and drug delivery. In an investigation for cancer cell therapy, Liu et al 18 examined that and are the best nanocomposites.…”

Cu and Cu-SWCNT Nanoparticles’ Suspension in Pulsatile Casson Fluid Flow via Darcy–Forchheimer Porous Channel with Compliant Walls: A Prospective Model for Blood Flow in Stenosed Arteries

“…Aside from that reported, the following recent studies, such as those by Souayeh et al [ 30 ], Ullah et al [ 31 ], and Aziz and Afify [ 32 ], can be referred to as additional knowledge correlated with the Casson NF flows. Dinarvand et al [ 33 ] demonstrated steady laminar mixed convection incompressible viscous and electrically conducting HNF (CuO- Cu/blood) flow over the plane stagnation point over a horizontal porous stretching layer with an external magnetic field, taking into account the induced magnetic field effect, which can be used in biomedical fields, especially in drug delivery. Reddy [ 34 ] investigated the model for electro-MHD flow over a stagnation point flow of HNF with non-linear thermal radiation and non-uniform heat source/sink that is implemented to blood-based NFs for two different NPs.…”

Bioconvection Due to Gyrotactic Microorganisms in Couple Stress Hybrid Nanofluid Laminar Mixed Convection Incompressible Flow with Magnetic Nanoparticles and Chemical Reaction as Carrier for Targeted Drug Delivery through Porous Stretching Sheet

“…In Bhatti’s study [ 7 ], the properties and implementations of the vector viscosity blood clot model were investigated. The two-step model of peristalsis was considered in Dinarvand [ 8 ]. The constant laminar-blended mixture viscous and hybrid (CUO-Cu/blood) hybrid fluid flows near the plane stagnations on a level, permeable, linearly stretched board with an adjustable magnetic flux through a new nanoparticle and based liquid measurement [ 9 ].…”