Improvement in moderate to severe vitiligo using a novel combination of 308 nm excimer laser and a surgical needling technique

BinSheikhan, S.; Abadie, Mohammed Al

doi:10.1111/ced.13056

Cited by 12 publications

(5 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In one study, 308-nm laser and microneedling yielded significantly better repigmentation than laser therapy alone. 14 A meta-analysis of 2 studies comparing NB-UVB and microneedling versus NB-UVB alone revealed lower odds of treatment failure (<25% repigmentation) with microneedling (OR 0.21, 95% CI 0.11–0.52, p = .0003) (see Supplemental Digital Content , Figure S1, http://links.lww.com/DSS/B91). 15,16 Side effects of microneedling were generally minimal and primarily included transient pain, pruritus, minor bleeding, and discomfort during or shortly after treatment.…”

Section: Resultsmentioning

confidence: 99%

Utilization of Our Toolkit: A Systematic Review and Meta-analysis of Surgical Therapies in Vitiligo Treatment

McCrary

Gibbs

Alharthi

et al. 2022

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

Utilization of Our Toolkit: A Systematic Review and Meta-analysis of Surgical Therapies in Vitiligo Treatment

McCrary

Gibbs

Alharthi

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Response to treatment was measured using the Global Assessment Score every four weeks for up to sixteen weeks. Results showed that Group 2 achieved a statistically higher score (P < 0.001) compared to Group 1 [4]. They concluded that the addition of needling technique fifteen minutes prior to exposure to the laser gave a significantly better result [4].…”

Section: Vitiligomentioning

confidence: 98%

“…Meanwhile, needling is the use of 27G needles to treat skin conditions such as vitiligo [4]. The size of the needle is larger than the microneedles in Dermaroller and Dermapen.…”

mentioning

confidence: 99%

Untitled

2018

IJCED

View full text Add to dashboard Cite

Introduction: Microneedling, needling and acupuncture are some of the upcoming treatment modalities used in the management conditions. It has been postulated that in microneedling and needling, superficial trauma to the epidermis leads to the production of inflammatory cascade, resulting in production of growth factors that lead to skin rejuvenation.Objective: Our aim of this review paper is to review the current evidence available for the efficacy of microneedling, needling and acupuncture in the management of skin conditions. Method:We reviewed 21 papers which were a combination of pilot studies, systematic reviews, randomised controlled trials and prospective studies. Protocol studies for systematic reviews and non-English publications were excluded in this review. Discussion:We found that microneedling and needling as adjunct therapies are more effective than monotherapy for the management of skin conditions. Meanwhile, the evidence on the efficacy of acupuncture in management of skin conditions is debatable. However, we noted that in all the papers we reviewed, sample sizes are small and risk of bias is high due to poor disclosure of methodology and poor blinding due to the practical nature of the interventions assessed. Conclusion:We conclude that although evidence has shown significant improvement in using microneedling and needling as adjunct therapies, large randomised controlled trials need to be held. This is similar to the evidence for acupuncture as well.

show abstract

“…Moreover, a possible mechanical migration of melanocytes from the pigmented borders to the depigmented areas has been postulated. [ 89‐91 ] The wounding action of chemical peels has been reported in patients with vitiligo. Treatment with 88% phenol peeling in stable vitiligo lesions produced a repigmentation of 82.5% of hairy sites and 81.3% of non‐hairy .…”

Section: Proposed Treatmentsmentioning

confidence: 99%

Involvement of non‐melanocytic skin cells in vitiligo

Bastonini

Bellei

Filoni

et al. 2019

Experimental Dermatology

View full text Add to dashboard Cite

Despite melanocytes are the key players in vitiligo, a continuous cross‐talk between epidermal and dermal cells may strictly affect their functionality, in both lesional skin and non‐lesional skin. Focusing on this interplay, we have reviewed existing literature supporting evidence on cellular and functional alterations of surrounding epidermal keratinocytes, extracellular matrix (ECM) proteins and fibroblasts in the underlying dermal compartment that may contribute to melanocyte disappearance in vitiligo. We have also examined some clinical and therapeutic aspects of the disease to sustain the non‐exclusive involvement of melanocytes within vitiligo. As a result, a different and more complex scenario has appeared that may enable to provide better understanding about origins and progress of vitiligo and that should be considered in the evaluation of new treatment approaches.

show abstract

Improvement in moderate to severe vitiligo using a novel combination of 308 nm excimer laser and a surgical needling technique

Abstract: Click https://www.wileyhealthlearning.com/ced.aspx for the corresponding questions to this CME article.

Cited by 12 publications

References 4 publications

Utilization of Our Toolkit: A Systematic Review and Meta-analysis of Surgical Therapies in Vitiligo Treatment

Utilization of Our Toolkit: A Systematic Review and Meta-analysis of Surgical Therapies in Vitiligo Treatment

Untitled

Involvement of non‐melanocytic skin cells in vitiligo

Contact Info

Product

Resources

About