Improvement in Infertility and Pregnancy Outcomes after Weight Loss Surgery

Patel, Jitesh A.; Colella, Joseph J.; Esaka, Emmanuel J.; Patel, Nilesh A.; Thomas, Ronald

doi:10.1016/j.mcna.2007.01.002

Cited by 43 publications

(29 citation statements)

References 54 publications

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“…Although nonsurgical weight loss in morbidly obese women has proven to improve fertility status (59)(60)(61), data on fertility after weight loss by bariatric surgery are still limited. An improvement in the fertility status after massive weight loss after bariatric surgery has been described, although the mechanisms for improved reproductive function are not well understood, and most studies have not distinguished between ovulatory and anovulatory obese women (62)(63)(64)(65).…”

Section: Bariatric Surgery and Fertility Statusmentioning

confidence: 99%

“…Haddow et al (86) reported three cases of fetal neural tube defects in women who underwent gastrojejunostomy. Recent studies, however, provide reassuring data on pregnancy outcomes after bariatric procedures (61,67,87). A decrease in maternal complications, such as diabetes mellitus and hypertensive disorders, and fetal complications like macrosomia can be achieved after bariatric surgery (64,65,67).…”

Section: Pregnancy After Bariatric Surgerymentioning

confidence: 99%

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Impact of bariatric surgery on female reproduction

Merhi

2009

Fertility and Sterility

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Section: Bariatric Surgery and Fertility Statusmentioning

confidence: 99%

Section: Pregnancy After Bariatric Surgerymentioning

confidence: 99%

Impact of bariatric surgery on female reproduction

Merhi

2009

Fertility and Sterility

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“…Preoperatively, these patients had a mean age of 31± 4.8 years (range, 22-39) and a mean BMI of 41±2.7 (range, [36][37][38][39][40][41][42][43][44][45]. Of these, four patients previously underwent in vitro fertilization (IVF), but this fertilization cycle failed.…”

Section: Resultsmentioning

confidence: 99%

“…Nevertheless, an interval of 2 years is recommended from surgery to pregnancy [45]. In fact, contraception is advised specifically during the period of maximum postoperative weight loss (12-18 months) to avoid potential risks of complications secondary to poor maternal nutritional status and promote optimal weight loss in the patient [42,44].…”

Section: Discussionmentioning

confidence: 99%

The Potential Role of Intragastric Balloon in the Treatment of Obese-Related Infertility: Personal Experience

et al. 2010

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The prevalence of people who are overweight or obese has increased dramatically in high-income countries over the past 20 years. There is a strong association between obesity and infertility, and weight loss can result in increased fecundity in obese women. The aim of this study is to demonstrate the potential role of intragastric balloon in the treatment of obese-related infertility. This is a retrospective study. A chart review of 27 obese women seen between September 2003 and July 2008 was performed. They all presented with the diagnosis of infertility and had undergone endoscopic intragastric balloon positioning. Among these women who tried unsuccessfully to become pregnant before weight loss, 15 became pregnant afterward. The pregnancies proceeded without complications and ended with live births. An improvement in the fertility status after weight loss has been described, although data on fertility after weight loss following bariatric surgery are still limited. The results obtained in our experience are not different from data reported in literature for bariatric surgery. Therefore, balloon treatment might be effective in young infertile obese women who wish to become pregnant.

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“…In view of the results of these 2 studies and studies investigating the ability of women to conceive and deliver normal infants post-bariatric surgery, it would appear that the anxiety over poor pregnancy outcomes may be allayed as long as the appropriate supplementation for likely nutritional deficiencies is implemented [14][15][16][17].…”

Section: Discussionmentioning

confidence: 99%

Pregnancy after prophylactic total gastrectomy

et al. 2010

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Hereditary diffuse gastric cancer is an autosomal dominant inherited cancer predisposition syndrome characterized by susceptibility to diffuse gastric and lobular breast cancers. Since current screening options for diffuse gastric cancer are ineffective, prophylactic total gastrectomy (PTG) is a recommended option for unaffected germline CDH1 mutation carriers. It is unknown whether pregnancy after surgery is possible or advisable due to potential maternal nutritional deficiencies. In this report we describe the pregnancy outcomes in three CDH1 mutation positive women after PTG and in a CDH1 mutation negative woman after total gastrectomy for early gastric cancer.

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Improvement in Infertility and Pregnancy Outcomes after Weight Loss Surgery

Cited by 43 publications

References 54 publications

Impact of bariatric surgery on female reproduction

Impact of bariatric surgery on female reproduction

The Potential Role of Intragastric Balloon in the Treatment of Obese-Related Infertility: Personal Experience

Pregnancy after prophylactic total gastrectomy

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