Improvement in Hemodynamics and Contractility With Multipoint Left Ventricular Pacing in Cardiac Resynchronization Therapy

Alonso, Pau; Andrés, Ana; Osca, Joaquín; Cano, Óscar; Carranza, María José Sancho-Tello de; Ros, José Olagüe de

doi:10.1016/j.rec.2014.06.006

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…It has several advantages: adequated pacing thresholds, greater electrocatheter stability with low rates of electrode displacement, infrequent pacing of the phrenic nerve, pacing from basal left ventricle positions-apparently with better performance and ability to pacing around the scar tissue of the myocardiumand improved cardiac output in the medium to long term. Multipoint stimulation improves cardiac contractility to a greater extent than classical biventricular pacing [51], with an increase in the left ventricular ejection fraction of 12.7% compared to 6.7% in classic resynchronization [52].…”

Section: Optimization Of Resynchronization Therapymentioning

confidence: 96%

Cardiac Resynchronization Therapy in Advanced Heart Failure: Predictors of Response and Optimization of Therapy

Ángel¹,

Alfonso²,

Ángeles³

2017

The Role of the Clinical Cardiac Electrophysiologist in the Management of Congestive Heart Failure

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Heart failure affects a high percentage of the population, especially older patients. Cardiac resynchronization therapy is indicated in some patients with advanced heart failure. However, 20-40% of patients with implanted resynchronization device have no clinical response. In this chapter, we review factors related with the absence of a clinical response, recent technological advances that can reduce the failure rate, and an algorithm for management of patients without a clinical response.

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Section: Optimization Of Resynchronization Therapymentioning

confidence: 96%

Cardiac Resynchronization Therapy in Advanced Heart Failure: Predictors of Response and Optimization of Therapy

Ángel¹,

Alfonso²,

Ángeles³

2017

The Role of the Clinical Cardiac Electrophysiologist in the Management of Congestive Heart Failure

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Clinical outcome of left ventricular multipoint pacing versus conventional biventricular pacing in cardiac resynchronization therapy: a systematic review and meta-analysis

Zheng

Ding

et al. 2018

Heart Fail Rev

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Cardiac resynchronization therapy (CRT) is an effective treatment for selected patients with systolic heart failure. Unlike conventional biventricular pacing (BIP), the left ventricular multipoint pacing (MPP) can increase the number of left ventricular pacing sites via a quadripolar lead positioned in the coronary sinus. This synthetic study was conducted to integratively and quantitatively evaluate the clinical outcome of MPP in comparison with BIP. We systematically searched the databases of EMBASE, Ovid medline, and Cochrane Library through May 2018 for studies comparing the clinical outcome of MPP with BIP in the patients who accepted CRT. Hospitalization for reason of heart failure, left ventricular eject fraction (LVEF), CRT response, all-cause morbidity, and cardiovascular death rate was collected for meta-analysis. A total of 11 studies with 29,606 participants were included in this meta-analysis. Compared with BIP group, MPP decreased heart failure hospitalization (OR, 0.41; 95% CI, 0.33 to 0.50; P < 0.00001), improved LVEF (mean difference, 4.97; 95% CI, 3.11 to 6.83; P < 0.00001), increased CRT response (OR, 3.64; 95% CI, 1.68 to 7.87; P = 0.001), and decreased all-cause morbidity (OR, 0.41; 95% CI, 0.26-0.66; P = 0.0002) and cardiovascular death rate (OR, 0.21; 95% CI, 0.11-0.40; P < 0.00001). The published literature demonstrates that MPP was more effective than BIP in the heart failure patients who accepted cardiac resynchronization therapy.

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Improvement in Hemodynamics and Contractility With Multipoint Left Ventricular Pacing in Cardiac Resynchronization Therapy

Cited by 2 publications

References 7 publications

Cardiac Resynchronization Therapy in Advanced Heart Failure: Predictors of Response and Optimization of Therapy

Cardiac Resynchronization Therapy in Advanced Heart Failure: Predictors of Response and Optimization of Therapy

Clinical outcome of left ventricular multipoint pacing versus conventional biventricular pacing in cardiac resynchronization therapy: a systematic review and meta-analysis

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